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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Influenza virus RNA's in the cytoplasm of chicken embryo cells treated with 3'-deoxyadenosine.

3'-Deoxyadenosine (75 to 100 mug/ml) permitted analysis of the cytoplasmic influencza virus-specific RNAs synthesized early in the replicative cycle-a phase that has hitherto been obscurred by host cell RNA synthesis. In addition, late in the cycle (6 to 8) complementary virus-specific RNA's were the predominantly labeled species, suggesting that higher concentrations of 3'-deoxyadenosine selectively inhibit influenza viral genome replication.[1]

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