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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

A novel photoaffinity probe for the LTD4 receptor.

A novel photoaffinity probe for the leukotriene D4 receptor (LTD4) is described. L-745310, which is structurally related to the potent LTD4 antagonist MK-0476 (Singulair), was found to selectively label a 43-kDa protein in guinea-pig lung membrane previously identified as the LTD4 receptor.[1]


  1. A novel photoaffinity probe for the LTD4 receptor. Gallant, M., Sawyer, N., Metters, K.M., Zamboni, R.J. Bioorg. Med. Chem. (1998) [Pubmed]
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