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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Kilpatrick, D.C.

Kilpatrick,

Phospholipid-binding activity of human mannan-binding lectin.

Some C-type lectins possess phospholipid-binding ability, which may be of physiological importance. Human mannan-binding lectin (MBL) was found to bind specifically to solid-phase phosphatidylserine (PS), phosphatidylinositol (PI) and phosphatidylcholine (PC), but not cardiolipin (CL), in a concentration-dependent manner. This property was inhibited by EDTA and by monosaccharides, and exhibited a similar pH dependence to the carbohydrate (mannan)-binding activity of MBL. These findings may be of immunological relevance.[1]

References

Phospholipid-binding activity of human mannan-binding lectin. Kilpatrick, D.C. Immunol. Lett. (1998) [Pubmed]

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