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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Motilin increases food intake in mice.

The effect of motilin on food intake was investigated in nonfood-deprived mice. A significant increase in food intake was observed 1 h after ICV administration of motilin (3 nmol/mouse) and continued for 2 h. This effect was attenuated markedly by the motilin receptor antagonist GM-109 (0.3-3 nmol/mouse) in a dose-related manner. GM-109 alone had no effect on food intake. These results indicate that motilin receptors are present in the brain and may have a role in the regulation of food intake.[1]

References

  1. Motilin increases food intake in mice. Asakawa, A., Inui, A., Momose, K., Ueno, N., Fujino, M.A., Kasuga, M. Peptides (1998) [Pubmed]
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