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Human MAFA has alternatively spliced variants.

Human mast cell function-associated antigen (MAFA) cDNA has been cloned. This molecule is similar to the rat form having an intracellular domain containing a putative immunoreceptor tyrosine inhibition motif and an extracellular C type lectin-like domain. However, in contrast to rat MAFA, the amino acid sequence suggests the presence of two additional extracellular N-linked glycosylation sites. In addition, alternative mRNA transcripts are observed that differ substantially from those found in the rat.[1]

References

  1. Human MAFA has alternatively spliced variants. Lamers, M.B., Lamont, A.G., Williams, D.H. Biochim. Biophys. Acta (1998) [Pubmed]
 
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