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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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From the cholinergic gene locus to the cholinergic neuron.

The cholinergic gene locus (CGL) was first identified in 1994 as the site (human chromosome 10q11.2) at which choline acetyltransferase and a functional vesicular acetylcholine transporter are co-localized. Here, we present recent neuroanatomical, developmental, and evolutionary insights into the chemical coding of cholinergic neurotransmission that have been gleaned from the study of the CGL, and its protein products VAChT and ChAT, which comprise a synthesis-sequestration pathway that functionally defines the cholinergic phenotype.[1]

References

  1. From the cholinergic gene locus to the cholinergic neuron. Weihe, E., Schäfer, M.K., Schütz, B., Anlauf, M., Depboylu, C., Brett, C., Chen, L., Eiden, L.E. J. Physiol. Paris (1998) [Pubmed]
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