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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

mraY is an essential gene for cell growth in Escherichia coli.

The synthesis of the murein precursor lipid I is performed by MraY. We have shown that mraY is an essential gene for cell growth. Cells depleted of MraY first swell and then lyse. The expression of mraY DNA in vitro produces a 40-kDa polypeptide detectable by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.[1]


  1. mraY is an essential gene for cell growth in Escherichia coli. Boyle, D.S., Donachie, W.D. J. Bacteriol. (1998) [Pubmed]
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