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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Electrophysiological localization of brain regions involved in perceptual memory.

Event-related potentials ( ERP) were recorded during perceptual discrimination and short-term memory, varying the interstimulus interval (1-10 s) in delayed spatial frequency discrimination. Accuracy of discrimination remained unimpaired across this time interval, but choice reaction times increased. A brain source localization (BESA) model showed that the activity of the parietal and right temporal sources increased with long retention intervals in a sequential activation pattern where a long-latency component of the parietal source specific to the memory condition was observed, the latency of which matched a memory-related increase in choice reaction times in the cognitive task. It is suggested that the temporal sources are involved in encoding and storage of visual information, and the parietal source is involved in memory retrieval.[1]


  1. Electrophysiological localization of brain regions involved in perceptual memory. Reinvang, I., Magnussen, S., Greenlee, M.W., Larsson, P.G. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. (1998) [Pubmed]
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