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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

A new antitumor agent: methyl sulfonium perchlorate of echinomycin.

Newly modified-echinomycin such as S-methylated sulfonium perchlorate of echinomycin (1), monosulfoxide (2), disulfoxid (3) and sulfone (4) have been prepared and evaluated for in vitro biological activities of cytotoxicity against P388, B16 and SNU-16 as well as in vivo antitumor activity against murine leukemia P388 and melanoma B16.[1]


  1. A new antitumor agent: methyl sulfonium perchlorate of echinomycin. Park, Y.S., Kim, Y.H., Kim, S.K., Choi, S.J. Bioorg. Med. Chem. Lett. (1998) [Pubmed]
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