Chemical Compound Review:
benzoxazol benzooxazole
Synonyms:
BENZOXAZOLE, Benzooxazole, benzoxazoline, SureCN7903, PubChem21884, ...
von Geldern,
Lai,
Gum,
Daly,
Sun,
Fry,
Abad-Zapatero,
Lavergne,
Fernandes,
Bréhu,
Sidhu,
Brézak,
Prévost,
Ducommun,
Contour-Galcera,
Varga,
Aki-Sener,
Yalcin,
Temiz-Arpaci,
Tekiner-Gulbas,
Cherepnev,
Molnar,
Sondhi,
Singh,
Kumar,
Lozach,
Meijer,
Akahoshi,
Ashimori,
Sakashita,
Yoshimura,
Imada,
Nakajima,
Mitsutomi,
Kuwahara,
Ohtsuka,
Fukaya,
Miyazaki,
Nakamura,
Lai,
Gum,
Daly,
Fry,
Hutchins,
Abad-Zapatero,
von Geldern,
Lifshitz,
Tamburu,
Suslensky,
Dubnikova,
Yoshida,
Shiokawa,
Kawano,
Ito,
Murakami,
Suzuki,
Sato,
- Orally active benzoxazole derivative as 5-HT3 receptor partial agonist for treatment of diarrhea-predominant irritable bowel syndrome. Yoshida, S., Shiokawa, S., Kawano, K., Ito, T., Murakami, H., Suzuki, H., Sato, Y. J. Med. Chem. (2005)
- Potent, orally active aldose reductase inhibitors related to zopolrestat: surrogates for benzothiazole side chain. Mylari, B.L., Beyer, T.A., Scott, P.J., Aldinger, C.E., Dee, M.F., Siegel, T.W., Zembrowski, W.J. J. Med. Chem. (1992)
- AJI9561, a new cytotoxic benzoxazole derivative produced by Streptomyces sp. Sato, S., Kajiura, T., Noguchi, M., Takehana, K., Kobayashi, T., Tsuji, T. J. Antibiot. (2001)
- Synthesis and microbiological activity of some N-(o-hydroxyphenyl)benzamides and phenylacetamides as the possible metabolites of antimicrobial active benzoxazoles: part II. Sener, E.A., Bingöl, K.K., Oren, I., Arpaci, O.T., Yaçin, I., Altanlar, N. Farmaco (2000)
- Induction of apoptosis and necrosis by resistance modifiers benzazoles and benzoxazines on tumour cell line mouse lymphoma L5718 Mdr+cells. Varga, A., Aki-Sener, E., Yalcin, I., Temiz-Arpaci, O., Tekiner-Gulbas, B., Cherepnev, G., Molnar, J. In Vivo (2005)
- Synthesis, structure-activity relationships, and pharmacokinetic profiles of nonpeptidic alpha-keto heterocycles as novel inhibitors of human chymase. Akahoshi, F., Ashimori, A., Sakashita, H., Yoshimura, T., Imada, T., Nakajima, M., Mitsutomi, N., Kuwahara, S., Ohtsuka, T., Fukaya, C., Miyazaki, M., Nakamura, N. J. Med. Chem. (2001)
- Catalytic turnover of substrate benzylamines by the quinone-dependent plasma amine oxidase leads to H2O2-dependent inactivation: evidence for generation of a cofactor-derived benzoxazole. Lee, Y., Shepard, E., Smith, J., Dooley, D.M., Sayre, L.M. Biochemistry (2001)
- Peptidyl alpha-ketoheterocyclic inhibitors of human neutrophil elastase. 2. Effect of varying the heterocyclic ring on in vitro potency. Edwards, P.D., Wolanin, D.J., Andisik, D.W., Davis, M.W. J. Med. Chem. (1995)
- Leukotriene D4 antagonists and 5-lipoxygenase inhibitors. Synthesis of benzoheterocyclic [(methoxyphenyl)amino]oxoalkanoic acid esters. Musser, J.H., Kubrak, D.M., Chang, J., DiZio, S.M., Hite, M., Hand, J.M., Lewis, A.J. J. Med. Chem. (1987)
- Molecular recognition between ligands and nucleic acids: novel pyridine- and benzoxazole-containing agents related to Hoechst 33258 that exhibit altered DNA sequence specificity deduced from footprinting analysis and spectroscopic studies. Bathini, Y., Rao, K.E., Shea, R.G., Lown, J.W. Chem. Res. Toxicol. (1990)
- Scope and mechanism of palladium-catalyzed amination of five-membered heterocyclic halides. Hooper, M.W., Utsunomiya, M., Hartwig, J.F. J. Org. Chem. (2003)
- Metabolism of 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2 (1H)-one (L-696,229), an HIV-1 reverse transcriptase inhibitor, by rat liver slices and in humans. Balani, S.K., Kauffman, L.R., Arison, B.H., Olah, T.V., Goldman, M.E., Varga, S.L., O'Brien, J.A., Ramjit, H.G., Rooney, C.S., Hoffman, J.M. Drug Metab. Dispos. (1994)
- FTIR study of specific binding interactions between DNA minor groove binding ligands and polynucleotides. Adnet, F., Liquier, J., Taillandier, E., Singh, M.P., Rao, K.E., Lown, J.W. J. Biomol. Struct. Dyn. (1992)
- Synthesis and evaluation of anticancer benzoxazoles and benzimidazoles related to UK-1. Kumar, D., Jacob, M.R., Reynolds, M.B., Kerwin, S.M. Bioorg. Med. Chem. (2002)
- A new 5-HT3 receptor ligand. II. Structure-activity analysis of 5-HT3 receptor agonist action in the gut. Yamada, M., Sato, Y., Kobayashi, K., Konno, F., Soneda, T., Watanabe, T. Chem. Pharm. Bull. (1998)
- Peptidyl alpha-ketoheterocyclic inhibitors of human neutrophil elastase. 3. In vitro and in vivo potency of a series of peptidyl alpha-ketobenzoxazoles. Edwards, P.D., Zottola, M.A., Davis, M., Williams, J., Tuthill, P.A. J. Med. Chem. (1995)
- Design, synthesis, and evaluation of alpha-ketoheterocycles as class C beta-lactamase inhibitors. Kumar, S., Pearson, A.L., Pratt, R.F. Bioorg. Med. Chem. (2001)
- Synthesis and biological evaluation of novel heterocyclic quinones as inhibitors of the dual specificity protein phosphatase CDC25C. Lavergne, O., Fernandes, A.C., Bréhu, L., Sidhu, A., Brézak, M.C., Prévost, G., Ducommun, B., Contour-Galcera, M.O. Bioorg. Med. Chem. Lett. (2006)
- Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode. von Geldern, T.W., Lai, C., Gum, R.J., Daly, M., Sun, C., Fry, E.H., Abad-Zapatero, C. Bioorg. Med. Chem. Lett. (2006)
- Vibrational analysis of structure activity relationships (SAR) in molecular binding. Pivonka, D. Applied spectroscopy. (2004)
- Synthesis, anti-inflammatory, analgesic and kinase (CDK-1, CDK-5 and GSK-3) inhibition activity evaluation of benzimidazole/benzoxazole derivatives and some Schiff's bases. Sondhi, S.M., Singh, N., Kumar, A., Lozach, O., Meijer, L. Bioorg. Med. Chem. (2006)
- Thermal reactions of benzoxazole. Single pulse shock tube experiments and quantum chemical calculations. Lifshitz, A., Tamburu, C., Suslensky, A., Dubnikova, F. The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment & general theory. (2006)
- Synthesis and pharmacological characterization of a new benzoxazole derivative as a potent 5-HT3 receptor agonist. López-Tudanca, P.L., Labeaga, L., Innerárity, A., Alonso-Cires, L., Tapia, I., Mosquera, R., Orjales, A. Bioorg. Med. Chem. (2003)
- Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase. Lai, C., Gum, R.J., Daly, M., Fry, E.H., Hutchins, C., Abad-Zapatero, C., von Geldern, T.W. Bioorg. Med. Chem. Lett. (2006)