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PRSS16  -  protease, serine, 16 (thymus)

Homo sapiens

Synonyms: Serine protease 16, TSSP, Thymus-specific serine protease
 
 
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Disease relevance of PRSS16

 

High impact information on PRSS16

 

Biological context of PRSS16

 

Anatomical context of PRSS16

  • Alternatively spliced transcripts of the thymus-specific protease PRSS16 are differentially expressed in human thymus [3].
 

Analytical, diagnostic and therapeutic context of PRSS16

References

  1. Polymorphisms in the gene encoding thymus-specific serine protease in the extended HLA complex: a potential candidate gene for autoimmune and HLA-associated diseases. Lie, B.A., Akselsen, H.E., Bowlus, C.L., Gruen, J.R., Thorsby, E., Undlien, D.E. Genes Immun. (2002) [Pubmed]
  2. Prss16 is not required for T-cell development. Cheunsuk, S., Lian, Z.X., Yang, G.X., Gershwin, M.E., Gruen, J.R., Bowlus, C.L. Mol. Cell. Biol. (2005) [Pubmed]
  3. Alternatively spliced transcripts of the thymus-specific protease PRSS16 are differentially expressed in human thymus. Luther, C., Wienhold, W., Oehlmann, R., Heinemann, M.K., Melms, A., Tolosa, E. Genes Immun. (2005) [Pubmed]
  4. Expression, genomic structure and mapping of the thymus specific protease prss16: a candidate gene for insulin dependent diabetes mellitus susceptibility. Cheunsuk, S., Sparks, R., Noveroske, J.K., Hsu, T., Justice, M.J., Gershwin, M.E., Gruen, J.R., Bowlus, C.L. J. Autoimmun. (2002) [Pubmed]
  5. Cloning of a novel MHC-encoded serine peptidase highly expressed by cortical epithelial cells of the thymus. Bowlus, C.L., Ahn, J., Chu, T., Gruen, J.R. Cell. Immunol. (1999) [Pubmed]
 
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