Gene Review:
HSPBP1 - HSPA (heat shock 70kDa) binding protein,...
Homo sapiens
Synonyms:
FES1, HSPBP, Heat shock protein-binding protein 1, Hsp70-binding protein 1, Hsp70-binding protein 2, ...
- Development of a sensitive assay for the measurement of antibodies against heat shock protein binding protein 1 (HspBP1): increased levels of anti-HspBP1 IgG are prevalent in HIV infected subjects. Papp, D., Prohászka, Z., Kocsis, J., Füst, G., Bánhegyi, D., Raynes, D.A., Guerriero, V. J. Med. Virol. (2005)
- Expression of the cochaperone HspBP1 is not coordinately regulated with Hsp70 expression. Gottwald, E., Herschbach, M., Lahni, B., Miesfeld, R.L., Kunz, S., Raynes, D.A., Guerriero, V. Cell Biol. Int. (2006)
- Regulation of Hsp70 function by HspBP1: structural analysis reveals an alternate mechanism for Hsp70 nucleotide exchange. Shomura, Y., Dragovic, Z., Chang, H.C., Tzvetkov, N., Young, J.C., Brodsky, J.L., Guerriero, V., Hartl, F.U., Bracher, A. Mol. Cell (2005)
- Mutational analysis of the hsp70-interacting protein Hip. Prapapanich, V., Chen, S., Toran, E.J., Rimerman, R.A., Smith, D.F. Mol. Cell. Biol. (1996)
- The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates alpha-synuclein degradation decisions between proteasomal and lysosomal pathways. Shin, Y., Klucken, J., Patterson, C., Hyman, B.T., McLean, P.J. J. Biol. Chem. (2005)
- BAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP. Arndt, V., Daniel, C., Nastainczyk, W., Alberti, S., Höhfeld, J. Mol. Biol. Cell (2005)
- The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulator. Alberti, S., Böhse, K., Arndt, V., Schmitz, A., Höhfeld, J. Mol. Biol. Cell (2004)
- Inhibition of Hsp70 ATPase activity and protein renaturation by a novel Hsp70-binding protein. Raynes, D.A., Guerriero, V. J. Biol. Chem. (1998)
- HspBP1, an Hsp70 cochaperone, has two structural domains and is capable of altering the conformation of the Hsp70 ATPase domain. McLellan, C.A., Raynes, D.A., Guerriero, V. J. Biol. Chem. (2003)
- HspBP1, a homologue of the yeast Fes1 and Sls1 proteins, is an Hsc70 nucleotide exchange factor. Kabani, M., McLellan, C., Raynes, D.A., Guerriero, V., Brodsky, J.L. FEBS Lett. (2002)
- Modulation of in vivo HSP70 chaperone activity by Hip and Bag-1. Nollen, E.A., Kabakov, A.E., Brunsting, J.F., Kanon, B., Höhfeld, J., Kampinga, H.H. J. Biol. Chem. (2001)
- Cell surface-bound heat shock protein 70 (Hsp70) mediates perforin-independent apoptosis by specific binding and uptake of granzyme B. Gross, C., Koelch, W., DeMaio, A., Arispe, N., Multhoff, G. J. Biol. Chem. (2003)
- Orthologs in Arabidopsis thaliana of the Hsp70 interacting protein Hip. Webb, M.A., Cavaletto, J.M., Klanrit, P., Thompson, G.A. Cell Stress Chaperones (2001)
- An androgen receptor NH2-terminal conserved motif interacts with the COOH terminus of the Hsp70-interacting protein (CHIP). He, B., Bai, S., Hnat, A.T., Kalman, R.I., Minges, J.T., Patterson, C., Wilson, E.M. J. Biol. Chem. (2004)
- Hsc/Hsp70 interacting protein (hip) associates with CXCR2 and regulates the receptor signaling and trafficking. Fan, G.H., Yang, W., Sai, J., Richmond, A. J. Biol. Chem. (2002)
- Identification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arrays. Grelle, G., Kostka, S., Otto, A., Kersten, B., Genser, K.F., Müller, E.C., Wälter, S., Böddrich, A., Stelzl, U., Hänig, C., Volkmer-Engert, R., Landgraf, C., Alberti, S., Höhfeld, J., Strödicke, M., Wanker, E.E. Mol. Cell Proteomics (2006)
- Molecular cloning of human p48, a transient component of progesterone receptor complexes and an Hsp70-binding protein. Prapapanich, V., Chen, S., Nair, S.C., Rimerman, R.A., Smith, D.F. Mol. Endocrinol. (1996)
- Human serum contains detectable levels of the Hsp70 cochaperone HspBP1 and antibodies bound to HspBP1. Raynes, D.A., Thomson, C.A., Stroster, J., Newton, T., Cuneo, P., Guerriero, V. Journal of immunoassay & immunochemistry. (2006)