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Gene Review:

PPP1CB - protein phosphatase 1, catalytic subunit,...

Homo sapiens

Synonyms: HEL-S-80p, PP-1B, PP1B, PP1beta, PPP1CD, ...

Huang, T. et al., Barker, H.M. et al., Prochazka, M. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on PPP1CB

No sequence abnormalities were detected in PPP1CB by Southern blot analysis or by single-stranded conformational polymorphism analysis of all eight coding exons [1].
An expression-upregulated gene for Meishan skeletal muscle, designated protein phosphatase 1, catalytic subunit, beta isoform (PPP1CB), was identified [2].
The derived amino acid sequence of PPP1CB has high homology with the PPP1CB of three species, Mus musculus (99%), human (99%) and mouse (100%) [2].
Porcine PPP1CB contains an open reading frame encoding 327 amino acid residues with 13 and 1763 nucleotides in the 5' and 3' untranslated regions, respectively [2].
The possible role of PPP1CB and its relation to porcine heterosis are discussed [2].

Biological context of PPP1CB

Three genes for protein phosphatase 1 map to different human chromosomes: sequence, expression and gene localisation of protein serine/threonine phosphatase 1 beta (PPP1CB) [3].
The gene for human PP1 beta (PPP1CB) was localised to chromosome 2 by analysis of somatic cell hybrid DNA and mapped to band q23 by fluorescence in situ hybridization [3].

References

Molecular and linkage analysis of type-1 protein phosphatase catalytic beta-subunit gene: lack of evidence for its major role in insulin resistance in Pima Indians. Prochazka, M., Mochizuki, H., Baier, L.J., Cohen, P.T., Bogardus, C. Diabetologia (1995) [Pubmed]
Identification of a differentially expressed gene PPP1CB between porcine Longissimus dorsi of Meishan and Large WhitexMeishan hybrids. Huang, T., Xiong, Y.Z., Lei, M.G., Xu, D.Q., Deng, C.Y. Acta Biochim. Biophys. Sin. (Shanghai) (2006) [Pubmed]
Three genes for protein phosphatase 1 map to different human chromosomes: sequence, expression and gene localisation of protein serine/threonine phosphatase 1 beta (PPP1CB). Barker, H.M., Brewis, N.D., Street, A.J., Spurr, N.K., Cohen, P.T. Biochim. Biophys. Acta (1994) [Pubmed]

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AgaP_AGAP003114	Anopheles gambiae str. PEST
TOPP3	Arabidopsis thaliana
TOPP7	Arabidopsis thaliana
PPP1CB	Bos taurus
gsp-1	Caenorhabditis elegans
PPP1CB	Canis lupus familiaris
ppp1cb	Danio rerio
flw	Drosophila melanogaster
PPP1CB	Gallus gallus
PPP1CB	Macaca mulatta
Ppp1cb	Mus musculus
Os06g0164100	Oryza sativa Japonica Group
PPP1CB	Pan troglodytes
Ppp1cb	Rattus norvegicus
ppp1cb	Xenopus (Silurana) tropicalis

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