Gene Review:
Txnip - thioredoxin interacting protein
Mus musculus
Synonyms:
1200008J08Rik, AA682105, Hyplip1, THIF, Tbp-2, ...
- Hepatocellular carcinoma in Txnip-deficient mice. Sheth, S.S., Bodnar, J.S., Ghazalpour, A., Thipphavong, C.K., Tsutsumi, S., Tward, A.D., Demant, P., Kodama, T., Aburatani, H., Lusis, A.J. Oncogene (2006)
- VDUP1 is required for the development of natural killer cells. Lee, K.N., Kang, H.S., Jeon, J.H., Kim, E.M., Yoon, S.R., Song, H., Lyu, C.Y., Piao, Z.H., Kim, S.U., Han, Y.H., Song, S.S., Lee, Y.H., Song, K.S., Kim, Y.M., Yu, D.Y., Choi, I. Immunity (2005)
- Vitamin D(3) up-regulating protein 1 (VDUP1) antisense DNA regulates tumorigenicity and melanogenesis of murine melanoma cells via regulating the expression of fas ligand and reactive oxygen species. Song, H., Cho, D., Jeon, J.H., Han, S.H., Hur, D.Y., Kim, Y.S., Choi, I. Immunol. Lett. (2003)
- Identification of novel molecular candidates for fatty liver in the hyperlipidemic mouse model, HcB19. Van Greevenbroek, M.M., Vermeulen, V.M., De Bruin, T.W. J. Lipid Res. (2004)
- Exenatide inhibits beta-cell apoptosis by decreasing thioredoxin-interacting protein. Chen, J., Couto, F.M., Minn, A.H., Shalev, A. Biochem. Biophys. Res. Commun. (2006)
- Positional cloning of the combined hyperlipidemia gene Hyplip1. Bodnar, J.S., Chatterjee, A., Castellani, L.W., Ross, D.A., Ohmen, J., Cavalcoli, J., Wu, C., Dains, K.M., Catanese, J., Chu, M., Sheth, S.S., Charugundla, K., Demant, P., West, D.B., de Jong, P., Lusis, A.J. Nat. Genet. (2002)
- Tumor suppressor VDUP1 increases p27(kip1) stability by inhibiting JAB1. Jeon, J.H., Lee, K.N., Hwang, C.Y., Kwon, K.S., You, K.H., Choi, I. Cancer Res. (2005)
- Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals. Hui, T.Y., Sheth, S.S., Diffley, J.M., Potter, D.W., Lusis, A.J., Attie, A.D., Davis, R.A. J. Biol. Chem. (2004)
- Increased lipogenesis and fatty acid reesterification contribute to hepatic triacylglycerol stores in hyperlipidemic Txnip-/- mice. Donnelly, K.L., Margosian, M.R., Sheth, S.S., Lusis, A.J., Parks, E.J. J. Nutr. (2004)
- Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function. Junn, E., Han, S.H., Im, J.Y., Yang, Y., Cho, E.W., Um, H.D., Kim, D.K., Lee, K.W., Han, P.L., Rhee, S.G., Choi, I. J. Immunol. (2000)
- An analysis of high glucose and glucosamine-induced gene expression and oxidative stress in renal mesangial cells. Cheng, D.W., Jiang, Y., Shalev, A., Kowluru, R., Crook, E.D., Singh, L.P. Arch. Physiol. Biochem. (2006)
- Thioredoxin-interacting protein (Txnip) is a critical regulator of hepatic glucose production. Chutkow, W.A., Patwari, P., Yoshioka, J., Lee, R.T. J. Biol. Chem. (2008)