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Gene Review

ZNF76  -  zinc finger protein 76

Homo sapiens

Synonyms: D6S229E, ZNF523, Zfp523, Zinc finger protein 523, Zinc finger protein 76
 
 
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Disease relevance of ZNF76

 

High impact information on ZNF76

 

Biological context of ZNF76

 

Anatomical context of ZNF76

 

Associations of ZNF76 with chemical compounds

 

Other interactions of ZNF76

  • Taken together, these findings demonstrate that ZNF76 and ZNF143 are two members of a same family of transactivator proteins [5].
 

Analytical, diagnostic and therapeutic context of ZNF76

References

  1. Transcriptional regulation of the mouse cytosolic chaperonin subunit gene Ccta/t-complex polypeptide 1 by selenocysteine tRNA gene transcription activating factor family zinc finger proteins. Kubota, H., Yokota, S., Yanagi, H., Yura, T. J. Biol. Chem. (2000) [Pubmed]
  2. Staf, a novel zinc finger protein that activates the RNA polymerase III promoter of the selenocysteine tRNA gene. Schuster, C., Myslinski, E., Krol, A., Carbon, P. EMBO J. (1995) [Pubmed]
  3. ZNF76, a novel transcriptional repressor targeting TATA-binding protein, is modulated by sumoylation. Zheng, G., Yang, Y.C. J. Biol. Chem. (2004) [Pubmed]
  4. ZNF143 mediates basal and tissue-specific expression of human transaldolase. Grossman, C.E., Qian, Y., Banki, K., Perl, A. J. Biol. Chem. (2004) [Pubmed]
  5. ZNF76 and ZNF143 are two human homologs of the transcriptional activator Staf. Myslinski, E., Krol, A., Carbon, P. J. Biol. Chem. (1998) [Pubmed]
  6. A testis-expressed Zn finger gene (ZNF76) in human 6p21.3 centromeric to the MHC is closely linked to the human homolog of the t-complex gene tcp-11. Ragoussis, J., Senger, G., Mockridge, I., Sanseau, P., Ruddy, S., Dudley, K., Sheer, D., Trowsdale, J. Genomics (1992) [Pubmed]
  7. Acetylation and alternative splicing regulate ZNF76-mediated transcription. Zheng, G., Yang, Y.C. Biochem. Biophys. Res. Commun. (2006) [Pubmed]
  8. Complex regulation of human neuronal nitric-oxide synthase exon 1c gene transcription. Essential role of Sp and ZNF family members of transcription factors. Saur, D., Seidler, B., Paehge, H., Schusdziarra, V., Allescher, H.D. J. Biol. Chem. (2002) [Pubmed]
  9. ZNF143 activates gene expression in response to DNA damage and binds to cisplatin-modified DNA. Ishiguchi, H., Izumi, H., Torigoe, T., Yoshida, Y., Kubota, H., Tsuji, S., Kohno, K. Int. J. Cancer (2004) [Pubmed]
 
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