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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 54 documents. Results 1 - 10.

Homo sapiens
Gene: ... of proteins, TACE, ADAM10 and ADAM9, all fulfil some of the criteria required of alpha- secretase. In situ...Disease relevance of ADAM10 MV- SMC exposed to chronic anoxia( 24- 48 hours) showed a decrease in expression of the 2 putative alpha- secretase enzymes, mature TACE( TNFalpha- converting enzyme) and ADAM10... / Synonyms: ADAM 10
Mus musculus
Gene: ... Disease relevance of Adam10 However, we found that tumors of sympathoadrenal origin, such as pheochromocytomas and neuroblastomas, overexpress Kuz. High impact information on Adam10 To illustrate the utility..., invertebrate models point towards a key role of the ADAM 10 orthologues Kuzbanian and sup- 17 in Notch... / Synonyms: ADAM 10
Gallus gallus
Gene: ... High impact information on ADAM10 When a dominant- negative metalloprotease- mutant form of ADAM 10 is expressed in the ectoderm or ADAM 10 expression is knocked down with morpholinos, morphogenesis and tissue specification are altered. Chick ADAM 10 is expressed in the developing dermatome and myotome of the somite...
Xenopus laevis
Gene: ... Disease relevance of ADAM10 When expressed in embryos, ADAM13 induces hyperplasia of the cement gland, whereas ADAM10 does not. High impact information on ADAM10 Using chimeric constructs, we find that the metalloprotease domain of ADAM10 can substitute for that of ADAM13, but that specificity for cement gland...
Bos taurus
Gene: ... Psychiatry related information on ADAM10 Nevertheless, it could be concluded that both, ADAM10 and ADAM10- dn mice are suitable control mice for the assessment of alpha- secretase- related effects in animal models of Alzheimer' s disease. High impact information on ADAM10 Endogenous alpha- secretase...
Rattus norvegicus
Gene: Synonyms: ADAM 10
MeSH term: ... and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells. Chemical compound and disease...
Danio rerio
Gene: Synonyms: adam10
Drosophila melanogaster
Gene: ... High impact information on Kul The metalloprotease Kuzbanian( ADAM10) mediates the transactivation of EGF receptor by G protein- coupled receptors. In the absence of Kul in the developing wing, the level... evidence has implicated SUP- 17, the ortholog of Drosophila Kuzbanian and mammalian ADAM10, as the protease... / Synonyms: ADAM10
Homo sapiens
Gene: ... High impact information on HPYR1 Gastric differential expression of selected known genes( amphiregulin and ADAM 10) and a novel gene( HPYR1) was confirmed in vivo in patients with H. pylori infection....

 

 
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