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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 197 documents. Results 1 - 10.

Homo sapiens
Gene: ... Disease relevance of ABCA1 ApoE secretion from HMDM of ABCA1- deficient patients with Tangier... of ABCA1 in the human hepatoma cell line HepG2 markedly reduced the transfer of phospholipids to apoA- I. Recently, a haplotype in ABCA1 gene was associated with increased risk of type II diabetes mellitus( DM...
Mus musculus
Gene: ... , and phosphatidylinositol+ phosphatidylserine( PI+ PS )/ PC were all much higher in HDL from Abca1 (-/-), compared to wild...Disease relevance of Abca1 This decrease was associated with a 3- to 4- fold reduction in ATP... disease. However, the possibly beneficial effects of specific upregulation of macrophage ABCA1...
Gallus gallus
Gene: ... High impact information on ABCA1 Moreover, we observed that repression of the Coup- Tfs ablated the activation of Abca1, and Abcg1 mRNA expression by the selective LXR agonist, T0901317. It remains unclear whether ABCA1 functions to efflux cholesterol across the basolateral or apical membrane of the intestine...
Bos taurus
Gene: ... High impact information on ABCA1 This work could open new avenues for elucidating a potential role of ABCA1 in sterol homeostasis in the bovine organism. The ATP- binding cassette transporter A1( ABCA1... of the putative ABCA1 promoter region revealed potential transcription factor binding sites associated with ABCA1...
Chemical compound: ... , however, did not bind to the immunoglobulin; apparently the binding site on apo B was lost. ABCA1..., regeneration after partial hepatectomy, and carcinogenesis and of hyperplastic nodules and hepatomas, all...
MeSH term: ... isolated from patients with Tangier disease, which is due to a genetic defect in ABCA1. Bacterial... and diabetes destabilize ABCA1 protein and decrease cholesterol export from macrophages. We report here on Mac... by all gram- negative bacteria, activates macrophages to release cytokines that are potentially lethal...
Arabidopsis thaliana
Gene: Synonyms: AtABCA1
MeSH term: ... . Age and residual cholesterol efflux affect HDL cholesterol levels and coronary artery disease in ABCA1...
Danio rerio
Gene: Synonyms: abca1
Chemical compound: ... - alpha increased to activate LXR- alpha, as evidenced by increased mRNA levels of ABCA1 and LPL. Cholic... nor fenofibrate altered hepatic ABCA1 mRNA levels....

 

 
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