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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 233 documents. Results 1 - 10.

Saccharomyces cerevisiae S288c
Gene: ... Disease relevance of GCN5 Crystal structure of a GCN5- related N- acetyltransferase: Serratia... origin by PCAF and GCN5 acetyltransferases: acetylation of large T antigen. Adenovirus E1A requires the yeast SAGA histone acetyltransferase complex and associates with SAGA components Gcn5 and Tra1. High... / Synonyms: Histone acetyltransferase GCN5
Drosophila melanogaster
Gene: ... High impact information on Pcaf In addition, dAda2a is part of Gcn5- independent complexes, which are concentrated at transcriptionally active regions on polytene chromosomes.... / Synonyms: GCN5; Gcn5/PCAF; Gcn5/Pcaf
Homo sapiens
Gene: ... , through a TBP- free TAF- containing complex and GCN5. High impact information on PCAF E4F1 and PCAF... with PCAF and another acetylase, GCN5, in HeLa cells. Associations of PCAF with chemical compounds... of coenzyme A( CoA ), we have compared the activities of the HAT domains of human PCAF and its GCN5 homologue... / Synonyms: GCN5; GCN5L
Arabidopsis thaliana
Gene: ... High impact information on GCN5 These results suggest that acetylation of specific histone Lys residues, regulated by GCN5, TAF1, and HD1, is required for light- regulated gene expression. GCN5 and TAF1... acetylation was dependent only on GCN5. Mutation of GCN5 resulted in a long- hypocotyl phenotype and reduced... / Synonyms: GCN5
Homo sapiens
Gene: ... treatment. Physical interactions of GCN5L2 GST pull- down analysis subsequently confirmed that all human... to varying degrees in all tissue types. Here we show that Myc co- recruits TRRAP and GCN5 via direct physical...Disease relevance of GCN5L2 The expression of human general control of amino acid synthesis protein... / Synonyms: GCN5; GCN5L2; Histone acetyltransferase GCN5
Plasmodium falciparum 3D7
Mus musculus
Gene: ... High impact information on Gcn5l2 Gcn5( encoded by Gcn5l2) and Pcaf, mouse histone acetyltransferases, share similar sequences and enzymatic activities. Loss of Gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development. In contrast, Gcn5l2- null embryos die during embryogenesis. Loss... / Synonyms: Gcn5; Gcn5l2; Histone acetyltransferase GCN5
MeSH term: ... : a homolog to yeast Gcn5p linking histone acetylation to gene activation. Upon activation of a specific... against various acetylated lysine residues on histones H3 and H4 showed that acetylation of all...
Homo sapiens
Gene: ... Gcn5- like HATs utilize an ordered sequential mechanism involving direct nucleophilic attack of the N...- epidermal interactions take place on this side of the scale. This cDNA, termed GCN5L1( GCN5- like 1... peptide having 23. 5% identity to yeast GCN5. Double- blind, placebo- controlled, randomized trial... / Synonyms: GCN5-like protein 1; GCN5L1
MeSH term: ... ). To investigate the role of substrate interactions in the differential behavior of free and complexed Gcn5p, sucrose density gradient centrifugation was used to characterize the binding of HAT A2 and free rGcn5p...


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