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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 158 documents. Results 1 - 10.

Homo sapiens
Gene: ... Disease relevance of HSF1 Gel mobility shift analysis revealed increased HSF1 activation..., but not in synovial tissue derived from patients with osteoarthritis. Like its counterpart in Drosophila, human HSF1..., suggesting that the intrinsic activity of HSF is under negative control in human cells. HSF1 is activated... / Synonyms: HSF 1
Mus musculus
Gene: ... in vivo remains elusive. All three mammalian HSFs( HSF1, HSF2, HSF4) have also been shown to be required...Disease relevance of Hsf1 Hsf1 -/- mice had greater hearing loss than Hsf1 +/+ mice... demonstrate that Hsf1 is critical for maintaining cellular integrity after heat stress and that cells from hsf... / Synonyms: HSF 1; Hsf1alpha; Hsf1beta
Caenorhabditis elegans
Gene: ... High impact information on hsf- 1 Down- regulation of hsf- 1 by RNA interference suppressed... of Caenorhabditis elegans to influence aging. hsf- 1 was also required for temperature- induced dauer larvae formation in an ILS mutant. The cyl- 1 mutants are essentially wild type in appearance, while hsf- 1 and sup...
Danio rerio
Gene: ... Disease relevance of hsf1 To characterize the role of zHSF1a and zHSF1b isoforms in the regulation...M) exposures in order to specify whether the disappearance of HSF1b is specific for heat stress. High impact information on hsf1 Suppression of heat shock transcription factor HSF1 in zebrafish causes heat- induced... / Synonyms: HSF1c; hsf1a; hsf1b
HSF1  -  Hsf1p
Saccharomyces cerevisiae S288c
Gene: ... Disease relevance of HSF1 A HSF1 mutant( hsf1- m3) which does not induce the expression of some... information on HSF1 Using a yeast heat shock gene flanked by mating- type silencers as a model system, we find... context of HSF1 The baker' s yeast Saccharomyces cerevisiae encodes a single HSF protein that responds...
Arabidopsis thaliana
Gene: ... Disease relevance of HSF1 The heat shock factor( HSF1) is the central regulator of the heat stress... response in Arabidopsis thaliana by transgenic expression of a chimaeric HSF1 protein fusion construct... peroxidase in Arabidopsis. Biological context of HSF1 The HSF1 kinase interacts with the cell- cycle control...
Rattus norvegicus
Gene: ... Disease relevance of Hsf1 Following heat stress, hearts from aged animals demonstrated a 47% reduction in Hsf1 activation, a reduction in Hsp72 mRNA and a 35% reduction in Hsp72 protein content, compared to hearts from adults. Hyperthermia resulted in stress- induced Hsf1 hyperphosphorylation...
Schizosaccharomyces pombe 972h-
MeSH term: ... identified this 140- 150- kD protein to be CD22. Gel mobility shift analysis revealed increased HSF1...
Gallus gallus
Gene: ... and loss of thermotolerance. HSF1 has the properties of a classical HSF and exhibits rapid activation... sequences of chicken HSF1 are highly conserved with human HSF1, but those of HSF3 diverge significantly... of the heat shock response and directly influences HSF1 activity. The vertebrate genome encodes a family...


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