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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 211 documents. Results 1 - 10.

Mus musculus
Gene: ... Disease relevance of Lyn Remarkably, CD19 deficiency suppressed the hyper- responsive phenotype of Lyn (-/-) B cells and autoimmunity characterized by serum autoantibodies and immune complex- mediated glomerulonephritis in Lyn (-/-) mice. This study also suggests that reduced activity of Lyn, a negative regulator... / Synonyms: Tyrosine-protein kinase Lyn; p53Lyn; p56Lyn
Rattus norvegicus
Gene: ... Disease relevance of Lyn However, the role of Lyn in infectious diseases is not clear. Here, we demonstrate that Lyn activation by phosphorylation significantly impacted invasion of an alveolar epithelial... lung pathogen affecting individuals with deficient lung immunity. Psychiatry related information on Lyn... / Synonyms: Tyrosine-protein kinase Lyn; p53Lyn; p56Lyn
Homo sapiens
Gene: ... Disease relevance of LYN These findings indicate that LYN can short- circuit conventional B cell... failure suggested that expression and/ or activation of LYN/ HCK occurs during disease progression. BCR- ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected... / Synonyms: Tyrosine-protein kinase Lyn; p53Lyn; p56Lyn
Gallus gallus
Gene: ... Disease relevance of LYN Lymphoma B- cells rendered deficient for LYN, SYK, or both by targeted... of the stimulation was lower than in wild- type cells. High impact information on LYN Introduction of the wild- type( but not a kinase domain mutant) mouse fyn gene into LYN- deficient B cells restored their EMF responsiveness...
Xenopus (Silurana) tropicalis
Gene
MeSH term: ... observed in a number of glioma, prostate, kidney and breast carcinoma cell lines or tumour specimens. All.... In parallel with IgG- induced elevations in intracellular cyclic AMP levels in the same cell line, all 20... ), insulin, cholera toxin( CT) and cAMP all stimulate the phosphorylation of proteins in the PC12 nerve- like...
Mus musculus
Gene: Synonyms: duplicated Lyn gene

 

 
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