Your search matched a total of 48 documents. Results 1 - 10.
Mus musculus
Gene: ... High impact information on Lhx3 LIM factor Lhx3 contributes to the specification of motor neuron and interneuron identity through cell- type- specific protein- protein interactions. Lhx3 is involved..., Lhx3 and Lhx4 act in a binary fashion during a brief period in development to specify the trajectory... / Synonyms: LIM/homeobox protein Lhx3
Homo sapiens
Gene: ... Disease relevance of LHX3 Thus, we hypothesized that mutations in one or both of the two human LHX3.... These studies demonstrate that mutations in the LHX3 isoforms impair their gene regulatory functions and support the hypothesis that defects in the LHX3 gene cause complex pituitary disease in humans. Mutations in the human... / Synonyms: LIM/homeobox protein Lhx3; M2-LHX3
Danio rerio
Gene: ... High impact information on lhx3 We show that Fgf3 signaling from the ventral diencephalon is required in a non- cell autonomous fashion to induce the expression of lim3, pit1 and other pituitary- specific genes in the underlying adenohypophyseal progenitor cells. Further, induction of islet1 and lim3... / Synonyms: LIM/homeobox protein Lhx3
Macaca mulatta
Gene: ... High impact information on LHX3 The LHX3 LIM homeodomain transcription factor is required for pituitary development and motor neuron specification. We show that, whereas Lhx3b is highly expressed in these Lhx3- dependent cell types, high levels of Lhx3a expression are restricted to alpha glycoprotein...
Gallus gallus
Gene: ... High impact information on LHX3 These early emerging patterns were compared and found to be consistent with those of the hatched chick retina, where the outer nuclear layer label for Lim3, Isl1 and Isl... homeodomain proteins, Lhx3 and Isl1 determines ventral motor neuron formation....
Sus scrofa
Gene: ... High impact information on LHX3 The Lhx3 binding consensus site confers Lhx3- dependent transcriptional activation to heterologous promoters. By site selection, we demonstrate that Lhx3 binds at high..., we studied the role of the LIM domains in DNA interaction by Lhx3, a protein that is essential...
MeSH term: ... in vivo. Mutant dynactin in motor neuron disease. LIM factor Lhx3 contributes to the specification... endothelial growth factor promoter causes motor neuron degeneration. Conversely, the misexpression of Lhx3... homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons. Analytical, diagnostic...
MeSH term: ... and protein interaction assays, we found that Lhx3 binds directly to the LIM cofactor NLI to trigger V2... as abnormal testicular differentiation. Lhx3 is involved in the generation of two adjacent, but distinct, cell... on the neuroprotective mechanism of mGlu( 1) receptor antagonists. At young ages, all homozygous spa animals were spastic...
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Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
