The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 266 documents. Results 1 - 10.

Homo sapiens
Gene: ... Disease relevance of MDM2 The cellular oncoprotein, Mdm2, binds to and downmodulates p53 function; its human homologue, MDM2, is amplified in certain human tumours, including sarcomas and gliomas. TP53... none showed amplification, but one had increased levels of MDM2 mRNA. Antisense therapy targeting MDM2... / Synonyms: E3 ubiquitin-protein ligase Mdm2; Oncoprotein Mdm2; p53-binding protein Mdm2
Mus musculus
Gene: ... Disease relevance of Mdm2 Mice lacking Mdm2 in the CNS developed hydranencephaly at embryonic day... affects irradiation- induced phosphorylation of Mdm2 and radioresistance of melanoma cells by perturbing the regulation of p53. Immunohistochemical analysis for Mdm2 and p53 proteins in methylcholanthrene- induced... / Synonyms: E3 ubiquitin-protein ligase Mdm2; Mdm-2; Oncoprotein Mdm2
Gallus gallus
Gene: ... High impact information on MDM2 Other p53- related genes including p21WAF1, p27Kip1, MDM- 2, and the p16INK4a alternate reading frame( ARF) sequence showed similar patterns of differential mRNA expression....
Felis catus
Gene: ... Disease relevance of MDM2 There was no significant difference in the expression of mdm2 m... lymphoma cell lines. High impact information on MDM2 Moreover, to explore whether mutational inactivation of the p53 gene or inactivation of the P53 protein caused by mdm2 gene overexpression, occurred...
Canis lupus familiaris
Gene: ... Disease relevance of MDM2 Analysis of p53 mutational events and MDM2 amplification in canine soft- tissue sarcomas. Mdm2 reactivity in reserve- like cells in adenomas showed wide variation, the immunoreactive cells ranging from 4 to 80%. In contrast to Mdm2 reactivity, each of 14 hyperplastic lesions...
Homo sapiens
Gene: ... Regulation of p53 and MDM2 activity by MTBP. A novel cellular protein( MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2. Telomere- binding TRF2/ MTBP attaches telomeres to the nuclear... of MTBP Assignment of the MDM2 binding protein gene( MTBP) to human chromosome band 8q24 by in situ... / Synonyms: Mdm2-binding protein
Danio rerio
Gene: Synonyms: E3 ubiquitin-protein ligase Mdm2; p53-binding protein Mdm2
MeSH term: ... blood cells were isolated by Southern- blot analysis methods to determine MDM2 gene amplification... of Mdm2 proteins were determined using an immunohistochemical assay with monoclonal antibody 2A10, and MDM2 gene amplifications were studied by Southern blotting. Expression of BCRP messenger RNA( m...
Homo sapiens
Gene: ... in all esophageal cancers, whereas MDM2 T309G G/ G was associated with a 7- fold increased risk of death... that negatively regulates PTEN via ubiquitination, a paradigm analogous to that of Mdm2 and p53. Furthermore, we... stabilized p53 by preventing MDM2- mediated p53 degradation in HRS cells. wt p53 stabilization and activation...


Links to contributing authors: Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
WikiGenes - Universities