Your search matched a total of 108 documents. Results 1 - 10.
Homo sapiens
Gene: ... - sensitive cell lines were all MGMT- poor. The correlation of UV sensitivity with BCNU cytotoxicity suggests...Disease relevance of MGMT We have recently demonstrated that the MGMT gene is silenced by promoter methylation in many human tumors, including colorectal carcinomas. In addition, MGMT loss associated...
Mus musculus
Gene: ... Disease relevance of Mgmt Eight weeks after exposure to this dose of MNU, 40% of MNU- treated Mgmt... selective and impacts O6- bG- mediated enhancement of BCNU toxicity. These MGMT -/- mice were most sensitive...- old mice and survivals at the 30th day were determined, LD50s of MGMT -/- and MGMT +/+ mice were 20... / Synonyms: MGMT
Rattus norvegicus
Gene: ... , all variants expressed O6- methylguanine- DNA methyltransferase activity, while both kinds of cells... in 10 hepatoma cell lines, all derived from Reuber H35 hepatoma but differing in their status...Disease relevance of Mgmt Treatment of rat hepatoma cells( H4 cells) with various DNA- damaging... / Synonyms: MGMT
Canis lupus familiaris
Gene: ... Disease relevance of MGMT Using MGMT selection, long- term marking levels exceeding 50% can now be routinely attained with minimal toxicity. High impact information on MGMT Proline at position 140 and the surrounding amino acids of the human MGMT are highly conserved in the canine sequence. The human O( 6...
Gallus gallus
Gene: ... High impact information on MGMT Relationship between the depletion of O6- methylguanine- DNA methyltransferase by O6- methylguanine and the stimulation of DNA synthesis and growth of cultured chick hepatocytes. O6- Methylguanine- DNA methyltransferase( O6- MT) has been described as a DNA repair enzyme...
MeSH term: ... transcript unexpectedly affects both the expression of all transcripts in the cluster and methylation of two... questioned. We examined gliomas to determine whether methylation of the MGMT promoter is related... molecular profiles, and assessment of MGMT promoter methylation might contribute to improved patient...
MeSH term: ... therapeutic decision- making. High impact information on Glioma RESULTS: The MGMT promoter was methylated... with carmustine( 1, 3- bis( 2- chloroethyl )- 1- nitrosourea, or BCNU). Inactivation of the DNA- repair gene MGMT...
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Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
