Your search matched a total of 64 documents. Results 1 - 10.
Homo sapiens
Gene: ... primers based on exon- flanking sequences amplify all SCN5A exons by PCR. Sequence analysis has indicated...Disease relevance of SCN5A SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome. Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses...
Canis lupus familiaris
Gene: ... Disease relevance of SCN5A BACKGROUND: This study examines the contribution of transmural... channel block under conditions mimicking HERG and SCN5A defects linked to the congenital long- QT syndrome( LQTS). High impact information on SCN5A Our aim was to determine if Na (+) currents and message...
Mus musculus
Gene: ... Disease relevance of Scn5a CONCLUSIONS: A 50% reduction in Scn5a expression alone or age- related interstitial fibrosis only slightly affects conduction. INTRODUCTION: Gain- of- function mutations within Scn5a.... High impact information on Scn5a Slowed conduction and ventricular tachycardia after targeted...
MeSH term: ... to SCN5A mutational analyses. Analytical, diagnostic and therapeutic context of Myocardium... and cardiac muscle, anti- MLCK decorated the actin- containing I bands of the sarcomere. Because all the known... milieu, and altered glycoside- binding properties of( Na++ K +)- ATPase all participate in the reduction...
MeSH term: ... Assessment( Health Care) MAIN OUTCOME MEASURES: Molecular and functional characterization of SCN5A defects... -- independently predicted all three outcome measures. The women underwent serial proton magnetic resonance...
MeSH term: ... in African Americans, SCN5A S1103Y. Similar high blood pressure accompanied by a low systemic renin state..., but there was significant heterogeneity in ORs among studies of African Americans( P <. 03). Here we studied SCN5A... additional mutations in the coding region of the CCR5 gene, all but 3 of which are codon altering or...
MeSH term: ... channel gene( SCN5A) defects have an increased frequency of cardiac events during sleep, and a recent case is reported of a sporadic SCN5A mutation in an infant with near SIDS, SCN5A has emerged as the leading... possessed SCN5A mutations: a 6- week- old white male with an A997S missense mutation in exon 17 and a 1...
MeSH term: ... intervals on baseline ECG in patients with established SCN5A mutations( PQ and HV interval and, upon class I...) and to the decrease in the extent of myocardial ischemia observed in all 12 ECG leads( r=- 0. 61) compared... trials. High impact information on Electrocardiography PATIENTS: All symptomatic patients who underwent...
MeSH term: ... the thin- filament contractile protein cardiac troponin T are responsible for 15% of all cases of familial hypertrophic cardiomyopathy, the leading cause of sudden death in young athletes. We have screened SCN5A... routinely applied to all infarct survivors with depressed ventricular function, a therapy that reduces...
MeSH term: ... . Role of SCN5A Y1102 polymorphism in sudden cardiac death in blacks. Analytical, diagnostic... doses of cocaine severely depressed all cardiac parameters and its effect on the isolated heart, cocaine... lower all- cause mortality( 30 vs. 49, HR= 0. 67, 95% CI 0. 42 to 1. 06, p= 0. 090) and fewer pacemaker...
Links to contributing authors:
Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
