Your search matched a total of 495 documents. Results 1 - 10.
Mus musculus
Gene: ... Disease relevance of Trp53 Mice inheriting two copies of this mutation( Trp53( 515C/ 515C )) escape the early onset of thymic lymphomas that characterize Trp53- null mice. Different Trp53 shRNAs produced... that paralleled Trp53 -/- lymphomagenesis in the E( mu )- Myc mouse. In contrast, here we present data that mice...
Mus musculus
Gene: ... Disease relevance of Trp53inp1 Stress- induced failure of cell death programs may lead... immunization with recombinant Sip protein. Psychiatry related information on Trp53inp1 Stress- induced... receptor- deficient mice. High impact information on Trp53inp1 Stress- induced activation of GADD34 feeds...
Mus musculus
Gene: ... High impact information on Trp53bp2 Its member ASPP2 was discovered more than 10 years ago as a binding partner of p53 and its role as a positive regulator of p53 mediated apoptosis has been clearly established in vitro....
Mus musculus
Gene: ... High impact information on Trp53inp2 Using ENU- induced mutagenesis, we discovered a new dominant Tcfap2a mutant named Doarad( Dor) that has a missense mutation in the PY motif of its transactivation.... Analytical, diagnostic and therapeutic context of Trp53inp2 Dor et al. investigated beta- cell renewal...
MeSH term: ... virus enhancer. Anatomical context of Oncogenes Both mutant and Trp53- null mouse embryonic fibroblasts... notably, by tightly regulating Trp53 knock- down using tetracycline- based systems, we show that cultured... by Trp53 suppression and cooperating oncogenes regress upon re- expression of Trp53. Gene context...
MeSH term: ... disease states, including leukemia and lymphoma. Mice inheriting two copies of this mutation( Trp53( 515C/ 515C )) escape the early onset of thymic lymphomas that characterize Trp53- null mice. Mice deficient... of Lymphoma The lymphomas and sarcomas that eventually developed in Trp53( 515C/ 515C) mice retained a diploid...
Mus musculus
Gene: ... High impact information on Trp53bp1 Using a human cell line that faithfully recapitulated the Chk2... genomic alterations that occur in B lymphocytes. Biological context of Trp53bp1 p53 Binding protein 53BP1... variant. Anatomical context of Trp53bp1 GFP- M protein forms foci in mouse embryonic fibroblast cells...
Homo sapiens
Gene: ... in all esophageal cancers, whereas MDM2 T309G G/ G was associated with a 7- fold increased risk of death... ") are observed in families with germline TP53 mutations: All families had at least one family member.... In our cohort, all patients with breast cancer under the age of 30 and a family history of a core cancer... / Synonyms: TRP53
MeSH term: ... inactivation of Trp53 partially rescues the demethylated fibroblasts for up to five population doublings... of these lesions has revealed that basic fibroblast growth factor( bFGF) is synthesized in all three stages...
MeSH term: ... goblet cell hyperplasia( GCH). Different Trp53 shRNAs produced distinct phenotypes in vivo, ranging from benign lymphoid hyperplasias to highly disseminated lymphomas that paralleled Trp53 -/- lymphomagenesis...
Links to contributing authors:
Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
