The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

SureCN713634     2-amino-5-[(2R,3R,4S,5R)-3,4- dihydroxy-5...

Synonyms: SureCN2779959, KST-1A6263, AC1L3YAJ, AK-20001, NSC279852, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on Pseudoisocytidine

  • Three other analogs of cytidine, containing a modification in the 5 position of the pyrimidine ring [5-aza-2'-deoxycytidine(5-aza-CdR), pseudoisocytidine (psi ICR) and 5-fluoro-2'-deoxycytidine(FCdR)] also induced the formation of muscle cells and inhibited DNA methylation [1].
  • Human leukemic cells in vitro deaminated psi ICyd very slowly, formed appreciable quantities of pseudoisocytidine triphosphate, and incorporated small amounts into RNA and DNA [2].
  • A group of 2'-fluoro and 5-substituted arabinosyl pyrimidines and a group of base-substituted pseudoisocytidine analogs were evaluated for their capacity to induce differentiation in the human promyelocytic leukemia cell line, HL-60 [3].

References

  1. Cellular differentiation, cytidine analogs and DNA methylation. Jones, P.A., Taylor, S.M. Cell (1980) [Pubmed]
  2. Biochemical, pharmacological, and phase I clinical evaluation of pseudoisocytidine. Woodcock, T.M., Chou, T.C., Tan, C.T., Sternberg, S.S., Philips, F.S., Young, C.W., Burchenal, J.H. Cancer Res. (1980) [Pubmed]
  3. Cell differentiation effects of 2'-fluoro-1-beta-D-arabinofuranosyl pyrimidines in HL-60 cells. Kong, X.B., Andreeff, M., Fanucchi, M.P., Fox, J.J., Watanabe, K.A., Vidal, P., Chou, T.C. Leuk. Res. (1987) [Pubmed]
 
WikiGenes - Universities