Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

FF-705 [(2R,3S,5R)-2- (acetyloxymethyl)-5-[5...

Synonyms: AG-G-96702, SureCN11142537, AC1L2QOC, AC1Q4KUR, CTK5E0101, ...

Takeshita, S. et al.

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Disease relevance of FF-705

At this dose, body weight gain was suppressed slightly when FF-705 was given alone, and this change was milder in the DFMO-supplemented group [1].

High impact information on FF-705

Moreover, maltase and diamine oxidase activities of intestinal epithelium remained higher with combined treatment than with FF-705 alone [1].

References

Alleviation of intestinal lesions by combined treatment with a 5-fluoro-2'-deoxyuridine (FUDR) derivative and alpha-difluoromethylornithine (DFMO)[correction of DMFO] in tumor-bearing mice. Takeshita, S., Nagatomi, H., Ando, K. Biochem. Pharmacol. (1992) [Pubmed]

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