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Chemical Compound Review:

BBAU 1-(2-hydroxyethoxymethyl)-5- [(3...

Synonyms: CHEMBL277577, CHEBI:39579, CHEBI:119633, AC1Q6CGT, AR-1G6750, ...

Lee, K.H. et al., Niedzwicki, J.G. et al.

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Disease relevance of 5-Bbau

Inhibition of nucleoside transport in murine lymphoma L5178Y cells and human erythrocytes by the uridine phosphorylase inhibitors 5-benzylacyclouridine and 5-benzyloxybenzylacyclouridine [1].

High impact information on 5-Bbau

5-benzylacyclouridine and 5-benzyloxybenzylacyclouridine, potent inhibitors of uridine phosphorylase [2].

Associations of 5-Bbau with other chemical compounds

The uridine phosphorylase inhibitors, 5-benzylacyclouridine (BAU) and 5-benzyloxybenzylacyclouridine (BBAU) (Biochem. Pharmacol., 31: 1857, 1982), inhibited uptake of uridine in L5178Y cells [1].

References

Inhibition of nucleoside transport in murine lymphoma L5178Y cells and human erythrocytes by the uridine phosphorylase inhibitors 5-benzylacyclouridine and 5-benzyloxybenzylacyclouridine. Lee, K.H., el Kouni, M.H., Chu, H.S., Cha, S. Cancer Res. (1984) [Pubmed]
5-benzylacyclouridine and 5-benzyloxybenzylacyclouridine, potent inhibitors of uridine phosphorylase. Niedzwicki, J.G., Chu, S.H., el Kouni, M.H., Rowe, E.C., Cha, S. Biochem. Pharmacol. (1982) [Pubmed]

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