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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Chemical Compound Review: 

AC1L3AUC     ethylbenzene

Synonyms: 1-phenyl-ethyl, 1-phenylethyl, 2348-51-8, 1-(phenyl)ethyl, 25956-EP2269990A1, ...
 
 
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High impact information on ethylbenzene

  • Transcriptomic analysis with a DNA microarray containing 70-mer probes for 8,213 RHA1 genes revealed a suite of 320 genes of diverse functions that were upregulated during growth both on BPH and on ETB, relative to growth on the control substrate, pyruvate [1].
  • To investigate the expression of these isozymes and better understand how they contribute to the robust degradative capacity of RHA1, we comprehensively analyzed the 9.7-Mb genome of RHA1 for BPH pathway genes and characterized the transcriptome of RHA1 growing on benzoate (BEN), BPH, and ETB [1].
  • The concentration of TOL, XYL and EBZ in blood was measured at various times (5, 30, 60, 90 and 120 min) following the end of exposure and the areas under the blood concentration curves (AUC) were calculated [2].

References

  1. Transcriptomic Assessment of Isozymes in the Biphenyl Pathway of Rhodococcus sp. Strain RHA1. Gonçalves, E.R., Hara, H., Miyazawa, D., Davies, J.E., Eltis, L.D., Mohn, W.W. Appl. Environ. Microbiol. (2006) [Pubmed]
  2. Comparison of the influence of binary mixtures versus a ternary mixture of inhaled aromatic hydrocarbons on their blood kinetics in the rat. Tardif, R., Charest-Tardif, G., Brodeur, J. Arch. Toxicol. (1996) [Pubmed]
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