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MeSH Review

Oligonucleotide Array Sequence Analysis

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Disease relevance of Oligonucleotide Array Sequence Analysis


Psychiatry related information on Oligonucleotide Array Sequence Analysis


High impact information on Oligonucleotide Array Sequence Analysis

  • Recent genetic approaches including gene chip technology have been used to elucidate the gene expression profile of hematopoietic stem cells and other progenitors [9].
  • From a saturated sampling of over half a million PET sequences, we characterized 65,572 unique p53 ChIP DNA fragments and established overlapping PET clusters as a readout to define p53 binding loci with remarkable specificity [10].
  • Using high-density oligonucleotide arrays representing essentially all nonrepetitive sequences on human chromosomes 21 and 22, we map the binding sites in vivo for three DNA binding transcription factors, Sp1, cMyc, and p53, in an unbiased manner [11].
  • DNA chip analyses show that only a few transcripts are down-regulated in abh1, several of which are implicated in ABA signaling [12].
  • High-density oligonucleotide arrays were used to analyze gene expression profiles at various times following BRCA1 induction [13].

Chemical compound and disease context of Oligonucleotide Array Sequence Analysis


Biological context of Oligonucleotide Array Sequence Analysis


Anatomical context of Oligonucleotide Array Sequence Analysis


Associations of Oligonucleotide Array Sequence Analysis with chemical compounds


Gene context of Oligonucleotide Array Sequence Analysis

  • Furthermore, DNA microarray analysis of BTN1 and btn1-delta strains revealed differential expression of two genes, with at least one, HSP30, involved in pH control [34].
  • Using hybridization, cloning techniques and cDNA array analysis to identify inducible neuroprotective genes, we found that neuronal survival correlates with increased expression of Ucp2 [35].
  • The same DNA microarrays were also used to identify genes whose expression was affected by deletion of the transcriptional co-repressor TUP1 or overexpression of the transcriptional activator YAP1 [36].
  • We have used high-density oligonucleotide arrays to identify genes in which expression changed in response to activation of E2F1, E2F2, and E2F3 [37].
  • Using mammary-enriched cDNA microarrays, we identified several genes that were preferentially expressed in MK-PTEN mammary tissue, including the IGF-binding protein-5 (Igfbp5) gene, and others whose expression was reduced, including the genes for c-Jun amino-terminal kinase [38].

Analytical, diagnostic and therapeutic context of Oligonucleotide Array Sequence Analysis


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  13. Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1. Harkin, D.P., Bean, J.M., Miklos, D., Song, Y.H., Truong, V.B., Englert, C., Christians, F.C., Ellisen, L.W., Maheswaran, S., Oliner, J.D., Haber, D.A. Cell (1999) [Pubmed]
  14. Evolutionary genomics of Staphylococcus aureus: insights into the origin of methicillin-resistant strains and the toxic shock syndrome epidemic. Fitzgerald, J.R., Sturdevant, D.E., Mackie, S.M., Gill, S.R., Musser, J.M. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  15. Identification of genes regulated by 2-methoxyestradiol (2ME2) in multiple myeloma cells using oligonucleotide arrays. Chauhan, D., Li, G., Auclair, D., Hideshima, T., Richardson, P., Podar, K., Mitsiades, N., Mitsiades, C., Li, C., Kim, R.S., Munshi, N., Chen, L.B., Wong, W., Anderson, K.C. Blood (2003) [Pubmed]
  16. Stanniocalcin 2 is an estrogen-responsive gene coexpressed with the estrogen receptor in human breast cancer. Bouras, T., Southey, M.C., Chang, A.C., Reddel, R.R., Willhite, D., Glynne, R., Henderson, M.A., Armes, J.E., Venter, D.J. Cancer Res. (2002) [Pubmed]
  17. Gene expression profiles of reactive astrocytes in dopamine-depleted striatum. Nakagawa, T., Schwartz, J.P. Brain Pathol. (2004) [Pubmed]
  18. Hepatocyte growth factor activator inhibitor 2/placental bikunin (HAI-2/PB) gene is frequently hypermethylated in human hepatocellular carcinoma. Fukai, K., Yokosuka, O., Chiba, T., Hirasawa, Y., Tada, M., Imazeki, F., Kataoka, H., Saisho, H. Cancer Res. (2003) [Pubmed]
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  21. The wp mutation of Glycine max carries a gene-fragment-rich transposon of the CACTA superfamily. Zabala, G., Vodkin, L.O. Plant Cell (2005) [Pubmed]
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  23. Inhibition of p53-induced apoptosis without affecting expression of p53-regulated genes. Lotem, J., Gal, H., Kama, R., Amariglio, N., Rechavi, G., Domany, E., Sachs, L., Givol, D. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
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  26. A Rsc3/Rsc30 zinc cluster dimer reveals novel roles for the chromatin remodeler RSC in gene expression and cell cycle control. Angus-Hill, M.L., Schlichter, A., Roberts, D., Erdjument-Bromage, H., Tempst, P., Cairns, B.R. Mol. Cell (2001) [Pubmed]
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  30. Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics. Kager, L., Cheok, M., Yang, W., Zaza, G., Cheng, Q., Panetta, J.C., Pui, C.H., Downing, J.R., Relling, M.V., Evans, W.E. J. Clin. Invest. (2005) [Pubmed]
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  33. SCF(Pof1)-ubiquitin and its target Zip1 transcription factor mediate cadmium response in fission yeast. Harrison, C., Katayama, S., Dhut, S., Chen, D., Jones, N., Bähler, J., Toda, T. EMBO J. (2005) [Pubmed]
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  35. Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma. Mattiasson, G., Shamloo, M., Gido, G., Mathi, K., Tomasevic, G., Yi, S., Warden, C.H., Castilho, R.F., Melcher, T., Gonzalez-Zulueta, M., Nikolich, K., Wieloch, T. Nat. Med. (2003) [Pubmed]
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  39. Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis. Zimmermann, N., King, N.E., Laporte, J., Yang, M., Mishra, A., Pope, S.M., Muntel, E.E., Witte, D.P., Pegg, A.A., Foster, P.S., Hamid, Q., Rothenberg, M.E. J. Clin. Invest. (2003) [Pubmed]
  40. Hypothalamic gene expression in reproductively photoresponsive and photorefractory Siberian hamsters. Prendergast, B.J., Mosinger, B., Kolattukudy, P.E., Nelson, R.J. Proc. Natl. Acad. Sci. U.S.A. (2002) [Pubmed]
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