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Chemical Compound Review:

LS-48226 4-(dichloro-methyl- silyl)butanenitrile

Synonyms: CTK4B1011, AKOS006221187, BRN 1750770, AC1L23WX, A804149, ...

Chung, B.C. et al., Jean, P.A. et al.

Jean, Gallavan, Kolesar, Siddiqui, Oxley, Meeks,

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Disease relevance of BRN 1750770

Chlorosilane acute inhalation toxicity and development of an LC50 prediction model [1].

High impact information on BRN 1750770

2. Solvent extracts of urine obtained with or without enzyme hydrolysis were analysed by gc/ms after derivatization with MSTFA/TMSCI (N-methyl-N-trimethylsilyl-trifluoroacetamide/trimethyl chlorosilane) [2].

References

Chlorosilane acute inhalation toxicity and development of an LC50 prediction model. Jean, P.A., Gallavan, R.H., Kolesar, G.B., Siddiqui, W.H., Oxley, J.A., Meeks, R.G. Inhalation toxicology. (2006) [Pubmed]
Identification of urinary metabolites of pyrilamine after oral administration to man. Chung, B.C., Kim, D.H., Jung, B.H., Eom, K., Slikker, W., Park, J. Xenobiotica (1994) [Pubmed]

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