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Chemical Compound Review

AG-J-28182     4-(butylcarbamoylsulfamoyl) benzoic acid

Synonyms: SureCN1478625, AC1Q6VNN, CTK4E8962, AR-1F9306, AR-1F9307, ...
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High impact information on Carboxytolbutamide


  1. Tolbutamide inhibits cAMP-dependent phosphorylation of liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Aoki, M., Kaku, K., Inoue, H., Matsutani, A., Kaneko, T. Diabetes (1992) [Pubmed]
  2. Effect of inflammation on the rabbit hepatic cytochrome P-450 isoenzymes: alterations in the kinetics and dynamics of tolbutamide. Parent, C., Bélanger, P.M., Jutras, L., du Souich, P. J. Pharmacol. Exp. Ther. (1992) [Pubmed]
  3. Tolbutamide, flurbiprofen, and losartan as probes of CYP2C9 activity in humans. Lee, C.R., Pieper, J.A., Frye, R.F., Hinderliter, A.L., Blaisdell, J.A., Goldstein, J.A. Journal of clinical pharmacology. (2003) [Pubmed]
  4. Quantitative determination of tolbutamide and its metabolites in human plasma and urine by high-performance liquid chromatography and UV detection. Hansen, L.L., Brøsen, K. Therapeutic drug monitoring. (1999) [Pubmed]
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