Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Actinomycin-V 2-amino-4,6-dimethyl-3-oxo-N- (7,11,14...

Synonyms: ACTINOMYCIN V, Actinomycin X2, Ambotz5500142, NSC-175006, AC1L4MLT, ...

Fujiwara, K. et al., el-Naggar, M.Y. et al.

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Disease relevance of NSC175006

Streptomyces nasri strain YG62 produces a broad-spectrum antibiotic designated actinomycin X2 [1].

High impact information on NSC175006

The ELISA with anti-AMD immunoglobulin G fraction as a solid phase and 7-aminoactino-mycin beta-D-galactosidase conjugate was specific to AMD as well as 7 AMD and showed 30% cross-reaction with actinomycin V, while no cross-reactivity was seen with drugs commonly used with AMD in combination chemotherapy for cancer treatment [2].

References

Correlation of actinomycin X2 to the lipid profile in static and shaken cultures of Streptomyces nasri strain YG62. el-Naggar, M.Y., el-Kersh, M.A., el-Sharaky, A.S. Microbios (1999) [Pubmed]
Enzyme-linked immunosorbent assay for the quantification of actinomycin D using beta-D-galactosidase as a label. Fujiwara, K., Saita, T., Takenawa, N., Matsumoto, N., Kitagawa, T. Cancer Res. (1988) [Pubmed]

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