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Chemical Compound Review

AMILORIDE     3,5-diamino-6-chloro-N...

Synonyms: Amiclaran, Amilorida, Amyloride, Midamor, Amiloridum, ...
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High impact information on AMILORIDE

  • When isolated from intact tissue and grown in primary culture or as immortalized cell lines, these cells tend to lose these Amil+ Na+ channels [1].
  • According to previous studies, amiloride-sensitive (Amil+) Na+ channels are present in apical membranes of airway epithelial cells [1].


  1. Culture-dependent expression of Na+ conductances in airway epithelial cells. Kunzelmann, K., Kathöfer, S., Hipper, A., Gruenert, D.C., Gregner, R. Pflugers Arch. (1996) [Pubmed]
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