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Chemical Compound Review:

N-Pbgd [2,3,4,5,6-pentahydroxyhexyl- [(4-propan-2...

Synonyms: AC1L4TRA, AC1Q7EOL, AR-1C2736, 111811-14-4, N-4-Isopropylbenzylglucamine dithiocarbamate

Kiyozumi, M. et al., Kojima, S. et al.

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Disease relevance of N-Pbgd

N-benzyl-D-glucamine dithiocarbamate and N-p-isopropylbenzyl-D-glucamine dithiocarbamate improve the protective effect of diethyldithiocarbamate against cadmium-induced testicular toxicity in rats [1].

High impact information on N-Pbgd

Sodium N-benzyl-D-glucamine dithiocarbamate (BGD), sodium N-p-methylbenzyl-D-glucamine dithiocarbamate (MBGD), and sodium N-p-isopropylbenzyl-D-glucamine dithiocarbamate (PBGD), which were recently synthesized, were evaluated for their efficacy in the distribution and excretion of cadmium in rats and mice exposed to cadmium [2].

References

N-benzyl-D-glucamine dithiocarbamate and N-p-isopropylbenzyl-D-glucamine dithiocarbamate improve the protective effect of diethyldithiocarbamate against cadmium-induced testicular toxicity in rats. Kojima, S., Sugimura, Y., Ono, H., Shimada, H., Funakoshi, T. Biol. Pharm. Bull. (1993) [Pubmed]
Comparison of effectiveness of 3 dithiocarbamates on excretion and distribution of cadmium in rats and mice. Kiyozumi, M., Nouchi, T., Honda, T., Kojima, S., Tsuruoka, M. Toxicology (1990) [Pubmed]

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