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Chemical Compound Review

Actinium-225     actinium

Synonyms: AC1L4Z7V, 225Ac, 14265-85-1, Actinium, isotope of mass 225
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Disease relevance of actinium


High impact information on actinium


Analytical, diagnostic and therapeutic context of actinium


  1. Targeted actinium-225 in vivo generators for therapy of ovarian cancer. Borchardt, P.E., Yuan, R.R., Miederer, M., McDevitt, M.R., Scheinberg, D.A. Cancer Res. (2003) [Pubmed]
  2. Alpha-particle emitting atomic generator (Actinium-225)-labeled trastuzumab (herceptin) targeting of breast cancer spheroids: efficacy versus HER2/neu expression. Ballangrud, A.M., Yang, W.H., Palm, S., Enmon, R., Borchardt, P.E., Pellegrini, V.A., McDevitt, M.R., Scheinberg, D.A., Sgouros, G. Clin. Cancer Res. (2004) [Pubmed]
  3. Immunotherapy for acute myeloid leukemia. Jurcic, J.G. Current oncology reports. (2005) [Pubmed]
  4. Improved in vivo stability of actinium-225 macrocyclic complexes. Deal, K.A., Davis, I.A., Mirzadeh, S., Kennel, S.J., Brechbiel, M.W. J. Med. Chem. (1999) [Pubmed]
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