Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Oxonamide 4,6-dioxo-1H-1,3,5-triazine- 2-carboxamide

Synonyms: AG-K-61307, ANW-46964, AK-80987, CTK5C9660, AR-1F8737, ...

Barrera, C.M. et al., Yonetani, Y. et al., Johnson, W.J. et al.

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Disease relevance of Oxonamide

The present study was done to evaluate the utility of allantoxanamide for investigating problems concerning hyperuricemia using rats [1].

Psychiatry related information on Oxonamide

Dose and time relationships between allantoxanamide-induced heightened serum uric acid and locomotor activity were investigated [2].

High impact information on Oxonamide

Allantoxanamide: a potent new uricase inhibitor in vivo [3].

Chemical compound and disease context of Oxonamide

Those doses of allantoxanamide which elevated serum uric acid produced time-dependent changes in locomotor activity [2].

References

Decreasing effect of allantoxanamide, a hyperuricemic agent on renal functions in rats. Yonetani, Y., Iwaki, K., Ogawa, Y. Jpn. J. Pharmacol. (1987) [Pubmed]
Hyperuricemia and locomotor activity in developing rats. Barrera, C.M., Hunter, R.E., Dunlap, W.P. Pharmacol. Biochem. Behav. (1989) [Pubmed]
Allantoxanamide: a potent new uricase inhibitor in vivo. Johnson, W.J., Chartrand, A. Life Sci. (1978) [Pubmed]

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