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Chemical Compound Review

D3PVP     1-[[10-(2- aminocarbonylethyl)-7...

Synonyms: V2257_SIGMA, AR-1B9638, d(D-3-Pal)VP, AC1L50NV, AC1Q5JC0, ...
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High impact information on d(D-3-Pal)VP

  • In HIT cell monolayers, the relative order of affinity of analogues in competition for binding with [3H]AVP was: dAVP > AVT = VP > V1a antagonist > OXY > dDAVP > V2 antagonist = d(D-3-Pal)VP, in parallel with their biological activity [1].
  • The potency of d(D-3-Pal)VP relative to VP was 1:134 in stimulating insulin secretion and 1:40 with respect to IP production [1].


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