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Chemical Compound Review:

Benzamide benzamide

Synonyms: Benzoylamide, Lopac-B-2009, SureCN16352, ARONIS003511, CHEMBL267373, ...

Coyne, T.M. et al., Ma, Y. et al., Sykes, B.M. et al.

Coyne, Marcus, Woodbury, Black,

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High impact information on benzamide

Changes in the phenylcarboxamide side chain or in C-methylation in the linking chain had little effect on the rate of cyclization [1].
MSCs were isolated from green fluorescent protein (GFP) transgenic rats and double-labeled with 5-bromo-2-deoxyuridine (BrdU) and bis benzamide (BBZ) prior to transplantation into the adult hippocampus or striatum [2].

Analytical, diagnostic and therapeutic context of benzamide

Moreover, use of the traditional cell labels BrdU and BBZ may provide a misleading index of donor survival and differentiation after transplantation [2].
In a search for radiopharmaceuticals with unique imaging applications using positron emission tomography (PET), we have also developed three new phenylcarboxamide analogues of FCWAY [3].

References

N-Substituted 2-(2,6-dinitrophenylamino)propanamides: novel prodrugs that release a primary amine via nitroreduction and intramolecular cyclization. Sykes, B.M., Atwell, G.J., Hogg, A., Wilson, W.R., O'Connor, C.J., Denny, W.A. J. Med. Chem. (1999) [Pubmed]
Marrow stromal cells transplanted to the adult brain are rejected by an inflammatory response and transfer donor labels to host neurons and glia. Coyne, T.M., Marcus, A.J., Woodbury, D., Black, I.B. Stem Cells (2006) [Pubmed]
Liquid chromatography-tandem mass spectrometry identification of metabolites of three phenylcarboxyl derivatives of the 5-HT(1A) antagonist, N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridyl) trans-4-fluorocyclohexanecarboxamide (FCWAY), produced by human and rat hepatocytes. Ma, Y., Lang, L., Kiesewetter, D.O., Eckelman, W.C. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2002) [Pubmed]

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