Chemical Compound Review:
MOLI000721 benzamide
Synonyms:
MOLI001068, AC1L9OUM
- Benzamide riboside induces apoptosis independent of Cdc25A expression in human ovarian carcinoma N.1 cells. Grusch, M., Rosenberger, G., Fuhrmann, G., Braun, K., Titscher, B., Szekeres, T., Fritzer-Skekeres, M., Oberhuber, G., Krohn, K., Hengstschlaeger, M., Krupitza, G., Jayaram, H.N. Cell Death Differ. (1999)
- Nicotinamide and nicotinamide analogues as antitumor promoters in mouse skin. Ludwig, A., Dietel, M., Schäfer, G., Müller, K., Hilz, H. Cancer Res. (1990)
- Stimulation of poly(ADP-ribosyl)ation during Ehrlich ascites tumor cell "starvation" and suppression of concomitant DNA fragmentation by benzamide. Wielckens, K., George, E., Pless, T., Hilz, H. J. Biol. Chem. (1983)
- Toxicity and efficacy of benzamide riboside in cancer chemotherapy models. Jayaram, H.N., Yalowitz, J.A., Arguello, F., Greene, J.F. Current medicinal chemistry. (2002)
- Radioiodinated N-(2-diethylaminoethyl)benzamide derivatives with high melanoma uptake: structure-affinity relationships, metabolic fate, and intracellular localization. Eisenhut, M., Hull, W.E., Mohammed, A., Mier, W., Lay, D., Just, W., Gorgas, K., Lehmann, W.D., Haberkorn, U. J. Med. Chem. (2000)
- Pharmacotoxicological aspects of levosulpiride. Rossi, F., Forgione, A. Pharmacol. Res. (1995)
- Suppression of breast cancer by chemical modulation of vulnerable zinc fingers in estrogen receptor. Wang, L.H., Yang, X.Y., Zhang, X., Mihalic, K., Fan, Y.X., Xiao, W., Howard, O.M., Appella, E., Maynard, A.T., Farrar, W.L. Nat. Med. (2004)
- Inhibitors of poly(adenosine diphosphate-ribose) synthesis: effect on other metabolic processes. Milam, K.M., Cleaver, J.E. Science (1984)
- Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality. Koh, D.W., Lawler, A.M., Poitras, M.F., Sasaki, M., Wattler, S., Nehls, M.C., Stöger, T., Poirier, G.G., Dawson, V.L., Dawson, T.M. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death. Ying, W., Sevigny, M.B., Chen, Y., Swanson, R.A. Proc. Natl. Acad. Sci. U.S.A. (2001)
- A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors. Saito, A., Yamashita, T., Mariko, Y., Nosaka, Y., Tsuchiya, K., Ando, T., Suzuki, T., Tsuruo, T., Nakanishi, O. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Organic affective syndrome associated with metoclopramide: case report. Weddington, W.W., Banner, A. The Journal of clinical psychiatry. (1986)
- Scintigraphic detection of melanoma metastases with a radiolabeled benzamide ([iodine-123]-(S)-IBZM). Maffioli, L., Mascheroni, L., Mongioj, V., Gasparini, M., Baldini, M.T., Seregni, E., Castellani, M.R., Cascinelli, N., Buraggi, G.L. J. Nucl. Med. (1994)
- Expression of Mycobacterium smegmatis pyrazinamidase in Mycobacterium tuberculosis confers hypersensitivity to pyrazinamide and related amides. Boshoff, H.I., Mizrahi, V. J. Bacteriol. (2000)
- Effects of tiapride in tardive dyskinesia. Pollak, P., Gaio, J.M., Hommel, M., Pellat, J., Perret, J. Psychopharmacology (Berl.) (1985)
- Cisapride 20 mg b.d. for preventing symptoms of GERD induced by a provocative meal. The CIS-USA-89 Study Group. Castell, D., Silvers, D., Littlejohn, T., Orr, W., Napolitano, J., Oleka, N., Jokubaitis, L. Aliment. Pharmacol. Ther. (1999)
- Preferential binding of benzo[a]pyrene diol epoxide to the linker DNA of human foreskin fibroblasts in S phase in the presence of benzamide. Kurian, P., Jeffrey, A.M., Milo, G.E. Proc. Natl. Acad. Sci. U.S.A. (1985)
- Deletion of transfected oncogenes from NIH 3T3 transformants by inhibitors of poly(ADP-ribose) polymerase. Nakayasu, M., Shima, H., Aonuma, S., Nakagama, H., Nagao, M., Sugimura, T. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Maintenance of ATP favours apoptosis over necrosis triggered by benzamide riboside. Grusch, M., Polgar, D., Gfatter, S., Leuhuber, K., Huettenbrenner, S., Leisser, C., Fuhrmann, G., Kassie, F., Steinkellner, H., Smid, K., Peters, G.J., Jayaram, H.N., Klepal, W., Szekeres, T., Knasmüller, S., Krupitza, G. Cell Death Differ. (2002)
- Response of postmitotic neurons to X-irradiation: implications for the role of DNA damage in neuronal apoptosis. Gobbel, G.T., Bellinzona, M., Vogt, A.R., Gupta, N., Fike, J.R., Chan, P.H. J. Neurosci. (1998)
- Potentiation of carcinogen-induced methotrexate resistance and dihydrofolate reductase gene amplification by inhibitors of poly(adenosine diphosphate-ribose) polymerase. Bürkle, A., Heilbronn, R., zur Hausen, H. Cancer Res. (1990)
- Cell cycle-dependent intervention by benzamide of carcinogen-induced neoplastic transformation and in vitro poly(ADP-ribosyl)ation of nuclear proteins in human fibroblasts. Kun, E., Kirsten, E., Milo, G.E., Kurian, P., Kumari, H.L. Proc. Natl. Acad. Sci. U.S.A. (1983)
- Facilitation of glutamate receptors enhances memory. Staubli, U., Rogers, G., Lynch, G. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Impairment of lymphocyte adhesion to cultured fibroblasts and endothelial cells by gamma-irradiation. Piela-Smith, T.H., Aune, T., Aneiro, L., Nuveen, E., Korn, J.H. J. Immunol. (1992)
- Pharmacological characterization of 5-hydroxytryptamine4(5-HT4) receptors positively coupled to adenylate cyclase in adult guinea pig hippocampal membranes: effect of substituted benzamide derivatives. Bockaert, J., Sebben, M., Dumuis, A. Mol. Pharmacol. (1990)
- Benzamide riboside, a recent inhibitor of inosine 5'-monophosphate dehydrogenase induces transferrin receptors in cancer cells. Szekeres, T., Sedlak, J., Novotny, L. Current medicinal chemistry. (2002)
- The histone deacetylase inhibitor MS-275 interacts synergistically with fludarabine to induce apoptosis in human leukemia cells. Maggio, S.C., Rosato, R.R., Kramer, L.B., Dai, Y., Rahmani, M., Paik, D.S., Czarnik, A.C., Payne, S.G., Spiegel, S., Grant, S. Cancer Res. (2004)
- Mechanism of c-fos induction by active oxygen. Amstad, P.A., Krupitza, G., Cerutti, P.A. Cancer Res. (1992)
- Thiourea-catalyzed asymmetric michael addition of activated methylene compounds to alpha,beta-unsaturated imides: dual activation of imide by intra- and intermolecular hydrogen bonding. Inokuma, T., Hoashi, Y., Takemoto, Y. J. Am. Chem. Soc. (2006)
- Role of human nucleoside transporters in the cellular uptake of two inhibitors of IMP dehydrogenase, tiazofurin and benzamide riboside. Damaraju, V.L., Visser, F., Zhang, J., Mowles, D., Ng, A.M., Young, J.D., Jayaram, H.N., Cass, C.E. Mol. Pharmacol. (2005)
- Transformation of NIH/3T3 to anchorage independence by H-ras is accompanied by loss of suppressor activity. Tolsma, S.S., Cohen, J.D., Ehrlich, L.S., Bouck, N.P. Exp. Cell Res. (1993)
- The benzamide M344, a novel histone deacetylase inhibitor, significantly increases SMN2 RNA/protein levels in spinal muscular atrophy cells. Riessland, M., Brichta, L., Hahnen, E., Wirth, B. Hum. Genet. (2006)
- Novel and selective small molecule stimulators of osteoprotegerin expression inhibit bone resorption. Onyia, J.E., Galvin, R.J., Ma, Y.L., Halladay, D.L., Miles, R.R., Yang, X., Fuson, T., Cain, R.L., Zeng, Q.Q., Chandrasekhar, S., Emkey, R., Xu, Y., Thirunavukkarasu, K., Bryant, H.U., Martin, T.J. J. Pharmacol. Exp. Ther. (2004)
- Benzamide and 4-amino 1,8 naphthalimide treatment inhibit telomerase activity by down-regulating the expression of telomerase associated protein and inhibiting the poly(ADP-ribosyl)ation of telomerase reverse transcriptase in cultured cells. Ghosh, U., Bhattacharyya, N.P. FEBS J. (2005)
- Inhibitors of histone deacetylase as new anticancer agents. Jung, M. Current medicinal chemistry. (2001)
- Dosimetry of iodine-123-epidepride: a dopamine D2 receptor ligand. Votaw, J.R., Ansari, M.S., Mason, N.S., Schmidt, D., de Paulis, T., Holburn, G., Clanton, J.A., Votaw, D.B., Manning, R.G., Kessler, R.M. J. Nucl. Med. (1995)
- Airborne chemistry coupled to Raman spectroscopy. Santesson, S., Johansson, J., Taylor, L.S., Levander, I.a., Fox, S., Sepaniak, M., Nilsson, S. Anal. Chem. (2003)
- Blocking Na(+)/H(+) exchange reduces [Na(+)](i) and [Ca(2+)](i) load after ischemia and improves function in intact hearts. An, J., Varadarajan, S.G., Camara, A., Chen, Q., Novalija, E., Gross, G.J., Stowe, D.F. Am. J. Physiol. Heart Circ. Physiol. (2001)
- N-(2-diethylaminoethyl)-4-[123I]iodobenzamide as a tracer for the detection of malignant melanoma: simple synthesis, improved labelling technique and first clinical results. Brandau, W., Kirchner, B., Bartenstein, P., Sciuk, J., Kamanabrou, D., Schober, O. European journal of nuclear medicine. (1993)