Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

CHEMBL424344 N-(1-hydroxy-1-phenyl-propan- 2-yl)-N...

Synonyms: AG-E-34488, LS-7597, AC1L1FQV, CTK0I1657, AKOS006275568, ...

Shimizu, H. et al., Tricker, A.R. et al.

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Disease relevance of N-Nitrosoephedrine

The mutagenicity of N-nitrosomethamphetamine (NMA) and N-nitrosoephedrine (NEP), which were synthesized in our laboratory, was examined by the modified pre-incubation method of Ames assay using Salmonella typhimurium TA100 and TA98 [1].

High impact information on N-Nitrosoephedrine

N-Nitrosoephedrine (NEP), another N-nitroso compound detected in nitrosated Ephedra altissima tea and NMAP are shown to exert mutagenic activity in the Salmonella/mammalian microsome mutagenicity (Ames) test [2].

References

Mutagenic activity of N-nitrosomethamphetamine and N-nitrosoephedrine. Shimizu, H., Takemura, N., Ando, H., Morita, M., Machida, K. Cancer Lett. (1983) [Pubmed]
2-(N-nitroso-N-methylamino)propiophenone, a direct acting bacterial mutagen found in nitrosated Ephedra altissima tea. Tricker, A.R., Wacker, C.D., Preussmann, R. Toxicol. Lett. (1987) [Pubmed]

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