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Chemical Compound Review:

NSC 293939 zinc phenyl-[(phenyldiazenyl...

Synonyms: 36539-81-8, Zinc dithizonate, Zinc dithiazonate, Zinc bis(dithizonate)

This record was replaced with 657262.

Kruczynski, D. et al., Sawada, M. et al., Stewart, G.R. et al., Frederickson, C.J. et al.

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High impact information on DITHIZONE

Zinc dithizonate staining in the cat hippocampus: relationship to the mossy-fiber neuropil and postnatal development [1].
In this paper we report that cholinergic deafferentation of the hippocampus causes a transient rise in mossy-fiber zinc, as measured by zinc-dithizonate histochemistry [2].
We found that rapid selective killing of Paneth cells took place after the intravenous (i.v.) injection of diphenylthiocarbazone (dithizone), a chelator forming a zinc dithizonate complex, in the rat [3].
During the maturation phase (from stage III onwards) the red coloured zinc dithizonate granules are observed in the mid piece and tail of elongated spermatids; the number and the stain intensity of zinc granules increase continuously till the stage VII [4].

References

Zinc dithizonate staining in the cat hippocampus: relationship to the mossy-fiber neuropil and postnatal development. Frederickson, C.J., Howell, G.A., Frederickson, M.H. Exp. Neurol. (1981) [Pubmed]
Cholinergic denervation-induced increase of chelatable zinc in mossy-fiber region of the hippocampal formation. Stewart, G.R., Frederickson, C.J., Howell, G.A., Gage, F.H. Brain Res. (1984) [Pubmed]
Selective killing of Paneth cells by intravenous administration of dithizone in rats. Sawada, M., Takahashi, K., Sawada, S., Midorikawa, O. International journal of experimental pathology. (1991) [Pubmed]
Zinc transport through residual bodies in the rat testis; a histochemical study. Kruczynski, D., Passia, D., Haider, S.G., Glassmeyer, M. Andrologia (1985) [Pubmed]

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