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Chemical Compound Review

Sulfoacetate     2-sulfoethanoic acid

Synonyms: Sulfonoacetate, PubChem13769, ACMC-20ajmg, CHEBI:50519, HSDB 2706, ...
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High impact information on HSDB 2706

  • Parenterally administered beta-sulfo[1-14C]lactate is mostly excreted in the urine, but 12% is metabolized via beta-sulfopyruvate and cysteinesulfonate to 14CO2 and taurine. beta-Sulfopyruvate is not excreted, and only traces of sulfoacetate, perhaps formed by oxidative decarboxylation, are detected [1].
  • A third mechanism of desulfonation is suggested: the hydrolysis of sulfoacetate [2].
  • Preparation of sulfoacetate derivatives of cellulose by direct esterification [3].


  1. Cysteinesulfonate and beta-sulfopyruvate metabolism. Partitioning between decarboxylation, transamination, and reduction pathways. Weinstein, C.L., Griffith, O.W. J. Biol. Chem. (1988) [Pubmed]
  2. Dissimilation of the C2 sulfonates. Cook, A.M., Denger, K. Arch. Microbiol. (2002) [Pubmed]
  3. Preparation of sulfoacetate derivatives of cellulose by direct esterification. Chauvelon, G., Buléon, A., Thibault, J.F., Saulnier, L. Carbohydr. Res. (2003) [Pubmed]
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