The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Indenol(7CI)     1H-inden-1-ol

Synonyms: AGN-PC-00G6ZM, SureCN197033, AG-F-99119, ACMC-20mc95, NSC-245861, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of NSC245861


High impact information on NSC245861

  • In addition to 1-indenol, indene was transformed to cis-indandiol with an enantiomeric excess of 45.2% of cis-(1S,2R)-indandiol over cis-(1R,2S)-indandiol, as revealed by chiral HPLC analysis [1].
  • After three rounds of mutagenesis and screening, mutant 1C4-3G was identified to have a threefold reduction in 1-indenol formation over the wild type (20% vs 60% of total products) and a 40% increase of product (cis-indandiol) yield [2].


  1. Indene bioconversion by a toluene inducible dioxygenase of Rhodococcus sp. I24. Priefert, H., O'Brien, X.M., Lessard, P.A., Dexter, A.F., Choi, E.E., Tomic, S., Nagpal, G., Cho, J.J., Agosto, M., Yang, L., Treadway, S.L., Tamashiro, L., Wallace, M., Sinskey, A.J. Appl. Microbiol. Biotechnol. (2004) [Pubmed]
  2. Directed evolution of toluene dioxygenase from Pseudomonas putida for improved selectivity toward cis-indandiol during indene bioconversion. Zhang, N., Stewart, B.G., Moore, J.C., Greasham, R.L., Robinson, D.K., Buckland, B.C., Lee, C. Metab. Eng. (2000) [Pubmed]
WikiGenes - Universities