Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Rutinose (2R,3R,4S,5S,6R)-6- [[(2R,3R,4R,5R,6S)-3,4...

Synonyms: SureCN117741, CHEBI:27522, CPD-12733, AC1L9B5D, C08247, ...

Lin, H.Y. et al., Bae, E.A. et al., Cesquini, M. et al.

Cesquini, Torsoni, Stoppa, Ogo,

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Disease relevance of Rutinose

The rutinose moiety of flavonoids should protect against the invasion of rotavirus into cells [1].

High impact information on Rutinose

Results of the present study provide scientific evidence to suggest that rutinose at C7 is a negative moiety in flavonoid inhibition of LPS-induced NO production, and that HO-1 is involved in the inhibitory mechanism of flavonoids on LPS-induced iNOS and NO production [2].
The presence of rutinose at position C(3) in rutin may impair its antioxidant effect [3].

References

In vitro inhibitory effect of some flavonoids on rotavirus infectivity. Bae, E.A., Han, M.J., Lee, M., Kim, D.H. Biol. Pharm. Bull. (2000) [Pubmed]
Anti-inflammatory effect of heme oxygenase 1: glycosylation and nitric oxide inhibition in macrophages. Lin, H.Y., Shen, S.C., Chen, Y.C. J. Cell. Physiol. (2005) [Pubmed]
t-BOOH-induced oxidative damage in sickle red blood cells and the role of flavonoids. Cesquini, M., Torsoni, M.A., Stoppa, G.R., Ogo, S.H. Biomed. Pharmacother. (2003) [Pubmed]

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