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Chemical Compound Review:

Ajugasterone C (2S,3R,5R,9R,10R,11R,13R,14S,1 7S)-17-[(2R...

Synonyms: AC1L9BQ2, C08811, 23044-80-6

Odinokov, V.N. et al., Bourne, P.C. et al.

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Disease relevance of Ajugasterone C

Three ecdysteroid 7,9(11)-dien-7-ones (dacryhainansterone, 25-hydroxydacryhainansterone and kaladasterone) were prepared by dehydration of the corresponding 11a-hydroxy ecdysteroids (ajugasterone C, turkesterone and muristerone A, respectively) [1].

Analytical, diagnostic and therapeutic context of Ajugasterone C

The biological activities of 3-epi-20-hydroxyecdysone (EC(50)=1.6 x 10(-7) M), taxisterone (EC(50)=9.5 x 10(-8) M) and ajugasterone C (EC(50)=6.2 x 10(-8) M) have been determined in the Drosophila melanogaster B(II) bioassay for ecdysteroid agonist activity [2].

References

Ecdysteroid 7,9(11)-dien-6-ones as potential photoaffinity labels for ecdysteroid binding proteins. Bourne, P.C., Whiting, P., Dhadialla, T.S., Hormann, R.E., Girault, J.P., Harmatha, J., Lafont, R., Dinan, L. J. Insect Sci. (2002) [Pubmed]
Phytoecdysteroids from the juice of Serratula coronata L. (Asteraceae). Odinokov, V.N., Galyautdinov, I.V., Nedopekin, D.V., Khalilov, L.M., Shashkov, A.S., Kachala, V.V., Dinan, L., Lafont, R. Insect Biochem. Mol. Biol. (2002) [Pubmed]

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