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Chemical Compound Review

Agnuside     [(1R,2S,6S,7S)-7-hydroxy-2- [(2S,3R,4S,5S...

Synonyms: CHEMBL483223, SureCN382107, MEGxp0_000767, NP-002211, ACon1_000039, ...
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High impact information on Agnuside

  • Both pedunculariside and agnuside showed preferential inhibition of COX-2, with IC50 values of 0.15 +/- 0.21 mg/ml and 0.026 +/- 0.015 mg/ml respectively, while having only small inhibitory effects on COX-1 [1].
  • A new iridoid, pedunculariside, together with the known iridoid agnuside were isolated from the butanol extract of Vitex peduncularis stem bark [1].


  1. Iridoids with anti-inflammatory activity from Vitex peduncularis. Suksamrarn, A., Kumpun, S., Kirtikara, K., Yingyongnarongkul, B., Suksamrarn, S. Planta Med. (2002) [Pubmed]
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