Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AC1L9N97 [(2R,3S,4R,5R)-5-(2-amino-6- oxo-3H-purin-9...

Synonyms: PGP, Guanosine-3',5'-Diphosphate

Bugrysheva, J.V. et al., Lenz, A. et al.

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Disease relevance of Guanosine-3',5'-Bisphosphate

The global transcriptional regulator (p)ppGpp (guanosine-3'-diphosphate-5'-triphosphate and guanosine-3',5'-bisphosphate, collectively) produced by the relA and spoT genes in Escherichia coli allows bacteria to adapt to different environmental stresses [1].

High impact information on Guanosine-3',5'-Bisphosphate

The complex formed between ribonuclease T1 (RNase T1) and guanosine-3',5'-bisphosphate (3',5'-pGp) crystallizes in the cubic space group I23 with alpha = 86.47 (4) A [2].

References

Borrelia burgdorferi rel is responsible for generation of guanosine-3'-diphosphate-5'-triphosphate and growth control. Bugrysheva, J.V., Bryksin, A.V., Godfrey, H.P., Cabello, F.C. Infect. Immun. (2005) [Pubmed]
X-ray analysis of cubic crystals of the complex formed between ribonuclease T1 and guanosine-3',5'-bisphosphate. Lenz, A., Heinemann, U., Maslowska, M., Saenger, W. Acta Crystallogr., B (1991) [Pubmed]

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