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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Chemical Compound Review: 

Rhodisin     [(2S,3R,4S)-4-[(2S,3R)-5,7- dihydroxy-2-(3...

Synonyms: CHEMBL422711, AG-K-64281, AC1LAF69, CTK7J8572, PB233'OG
 
 
 
 
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High impact information on PB233'OG

  • Our study reports here for the first time that the induction of p21/WAF1 and activity of the Fas/Fas ligand apoptotic system may participate in the anti-proliferative activity of PB233'OG in A549 cells [1].
  • An enhancement in Fas/APO-1 and its two form ligands, membrane-bound Fas ligand (mFasL) and soluble Fas ligand (sFasL), might be responsible for the apoptotic effect induced by PB233'OG [1].
  • The results showed that PB233'OG inhibited the proliferation of A549 by blocking cell cycle progression in the G0/G1 phase and inducing apoptosis [1].

References

  1. Prodelphinidin B-2 3,3'-di-O-gallate from Myrica rubra inhibits proliferation of A549 carcinoma cells via blocking cell cycle progression and inducing apoptosis. Kuo, P.L., Hsu, Y.L., Lin, T.C., Lin, C.C. Eur. J. Pharmacol. (2004) [Pubmed]
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