Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

ApApA(Rp)A (2R,3R,4S,5R)-2-(6- aminopurin-9-yl)-5...

Synonyms: ApApA(Sp)A, AC1L9U62

This record was replaced with 501020.

Sobol, R.W. et al.

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High impact information on

ApA(Rp)A, ApA(Sp)A, ApApA(Rp)A, and ApApA(Sp)A are potent inhibitors of HIV-1-induced syncytia formation (80-, 10-, 40-, and 15-fold more inhibitory, respectively, than solvent control) [1].

References

Inhibition of HIV-1 replication and activation of RNase L by phosphorothioate/phosphodiester 2',5'-oligoadenylate derivatives. Sobol, R.W., Henderson, E.E., Kon, N., Shao, J., Hitzges, P., Mordechai, E., Reichenbach, N.L., Charubala, R., Schirmeister, H., Pfleiderer, W. J. Biol. Chem. (1995) [Pubmed]

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